UniProt Q8TEP8
Centrosomal protein of 192 kDa (Q8TEP8)
Centrosomal protein of 192 kDa (UniProt Q8TEP8): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 5 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8TEP8
- Protein
- Centrosomal protein of 192 kDa
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 5 · 1 record with a druggable one
Structures
5 records of Q8TEP8 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FVI | Ash / papd-like domain of human CEP192 (papd-like domain 7) | x-ray diffraction | A | CL | — |
| 6W3J | Crystal structure of the FAM46C/PLK4/CEP192 complex | x-ray diffraction | C | — | — |
| 7PTB | Crystal structure of the spd-2 domain of human CEP192 | x-ray diffraction | A | NO3 | — |
| 8PR7 | Aurora-A in complex with CEP192 and an inhibitory monobody | x-ray diffraction | C, F | — | 5 (best 0.70) |
| Q8TEP8 | AlphaFold monomer V2.0 prediction for centrosomal protein of 192 kda (Q8TEP8) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7PTB chain A against the predicted model Q8TEP8: TM-score 0.89, RMSD 2.62 Å
- 6FVI chain A against the predicted model Q8TEP8: TM-score 0.88, RMSD 1.84 Å
- 8PR7 chain F against the predicted model Q8TEP8: TM-score 0.46, RMSD 2.47 Å
- 6W3J chain C against the predicted model Q8TEP8: TM-score 0.45, RMSD 2.31 Å
- 8PR7 chain C against the predicted model Q8TEP8: TM-score 0.36, RMSD 3.52 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.