UniProt Q8Q8V9
HIV-1 protease (Q8Q8V9)
HIV-1 protease (UniProt Q8Q8V9), EC 3.4.23.16: 4 experimental structures on GenesisL1, 3 ligands bound, 3 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8Q8V9
- Protein
- HIV-1 protease
- EC
- 3.4.23.16
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 3 · 1 record with a druggable one
Structures
4 records of Q8Q8V9 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5VJ3 | HIV Protease (PR) in open form with Mg2+ in active site and HIVE-9 in eye site | x-ray diffraction | A | HV9, MG | 2 (best 0.49) |
| 5VJ3 | HIV protease (pr) in open form with MG2+ in active site and hive-9 in eye site | x-ray diffraction | A | HV9 | — |
| 5W5W | HIV Protease (PR) in open form with Mg2+ in active site and HIVE-9 in eye site | x-ray diffraction | A, B | 3TL, HV9 | 1 (best 0.72) |
| 5W5W | HIV protease (pr) in open form with MG2+ in active site and hive-9 in eye site | x-ray diffraction | A, B | 3TL, HV9 | — |
Ligands
- HV9 · 4-methyl-N-({1-[4-(trifluoromethyl)pyrimidin-2-yl]piperidin-4-yl}carbamoyl)benzene-1-sulfonamide · in 4 records
- 3TL · benzyl [(1S,4S,7S,8R,9R,10S,13S,16S)-7,10-dibenzyl-8,9-dihydroxy-1,16-dimethyl-4,13-bis(1-methylethyl)-2,5,12,15,18-pentaoxo-20-phenyl-19-oxa-3,6,11,14,17-pentaazaicos-1-yl]carbamate · in 2 records
- MG · Magnesium ion · in 1 record
Elsewhere
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