UniProt Q8NNJ2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (Q8NNJ2)
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex (UniProt Q8NNJ2), EC 2.3.1.12: 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 28 pockets. Binding sites…
- UniProt
- Q8NNJ2
- Protein
- Dihydrolipoyllysine-residue acetyltransferase component of pyruvate…
- EC
- 2.3.1.12
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 28 · 5 records with a druggable one
Structures
9 records of Q8NNJ2 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6ZZI | Crystal structure of the catalyic domain of Corynebacterium glutamicum acetyltransferase AceF (E2p). | x-ray diffraction | A, B, C, D, E, F | — | 15 (best 0.84) |
| 6ZZI | Crystal structure of the catalyic domain of corynebacterium glutamicum acetyltransferase acef (E2P). | x-ray diffraction | A, B, C, D, E, F | — | — |
| 6ZZJ | Crystal structure of the catalytic domain of Corynebacterium glutamicum acetyltransferase AceF… | x-ray diffraction | A | CAO | 1 (best 0.65) |
| 6ZZJ | Crystal structure of the catalytic domain of corynebacterium glutamicum acetyltransferase acef… | x-ray diffraction | A | CAO | — |
| 6ZZK | Crystal structure of the catalytic domain of C. glutamicum AceF (E2p) in ternary complex with CoA… | x-ray diffraction | A, B | COA, LPM | 3 (best 0.74) |
| 6ZZK | Crystal structure of the catalytic domain of C. glutamicum acef (E2P) in ternary complex with CoA… | x-ray diffraction | A, B | COA, LPM | — |
| 6ZZL | Crystal structure of the catalytic domain plus N-terminal linker of the acetyltransferase AceF… | x-ray diffraction | A, B, C | PO4 | 8 (best 0.82) |
| 6ZZL | Crystal structure of the catalytic domain plus N-terminal linker of the acetyltransferase acef… | x-ray diffraction | A, B, C | PO4 | — |
| Q8NNJ2 | AlphaFold monomer V2.0 prediction for dihydrolipoyllysine-residue acetyltransferase component of… | predicted | A | — | 1 (best 0.72) |
Ligands
Experiment against prediction
- 6ZZI chain F against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.56 Å
- 6ZZI chain E against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.58 Å
- 6ZZI chain B against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.58 Å
- 6ZZI chain B against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.58 Å
- 6ZZI chain C against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.62 Å
- 6ZZI chain C against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.62 Å
- 6ZZI chain A against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.77 Å
- 6ZZI chain A against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.77 Å
- 6ZZL chain B against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.73 Å
- 6ZZL chain B against the predicted model Q8NNJ2: TM-score 0.99, RMSD 0.73 Å
Elsewhere
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