UniProt Q8NHP6
Motile sperm domain-containing protein 2 (Q8NHP6)
Motile sperm domain-containing protein 2 (UniProt Q8NHP6): 6 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q8NHP6
- Protein
- Motile sperm domain-containing protein 2
- Experimental structures
- 6
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 20 · 2 records with a druggable one
Structures
7 records of Q8NHP6 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6TQS | The crystal structure of the MSP domain of human MOSPD2 in complex with the conventional FFAT motif… | x-ray diffraction | A, B, C, D, E, F | SO4, CL | 10 (best 0.63) |
| 6TQS | The crystal structure of the msp domain of human MOSPD2 in complex with the conventional ffat motif… | x-ray diffraction | A, B, C, D, E, F | SO4, CL | — |
| 6TQT | The crystal structure of the MSP domain of human MOSPD2. | x-ray diffraction | A | PO4 | 1 (best 0.37) |
| 6TQT | The crystal structure of the msp domain of human MOSPD2. | x-ray diffraction | A | PO4 | — |
| 6TQU | The crystal structure of the MSP domain of human MOSPD2 in complex with the Phospho-FFAT motif of… | x-ray diffraction | A, B | SO4 | 4 (best 0.46) |
| 6TQU | The crystal structure of the msp domain of human MOSPD2 in complex with the phospho-ffat motif of… | x-ray diffraction | A, B | SO4 | — |
| Q8NHP6 | AlphaFold monomer V2.0 prediction for motile sperm domain-containing protein 2 (Q8NHP6) | predicted | A | — | 5 (best 0.80) |
Ligands
Experiment against prediction
- 6TQU chain A against the predicted model Q8NHP6: TM-score 0.95, RMSD 1.69 Å
- 6TQU chain A against the predicted model Q8NHP6: TM-score 0.95, RMSD 1.69 Å
- 6TQU chain B against the predicted model Q8NHP6: TM-score 0.94, RMSD 1.72 Å
- 6TQU chain B against the predicted model Q8NHP6: TM-score 0.94, RMSD 1.72 Å
- 6TQT chain A against the predicted model Q8NHP6: TM-score 0.93, RMSD 1.62 Å
- 6TQT chain A against the predicted model Q8NHP6: TM-score 0.93, RMSD 1.62 Å
- 6TQS chain E against the predicted model Q8NHP6: TM-score 0.93, RMSD 1.86 Å
- 6TQS chain E against the predicted model Q8NHP6: TM-score 0.93, RMSD 1.86 Å
- 6TQS chain D against the predicted model Q8NHP6: TM-score 0.92, RMSD 1.80 Å
- 6TQS chain D against the predicted model Q8NHP6: TM-score 0.92, RMSD 1.80 Å
Elsewhere
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