UniProt Q8NFF5
Isoform 2 of FAD synthase (Q8NFF5)
Isoform 2 of FAD synthase (UniProt Q8NFF5), EC 2.7.7.2: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 21 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8NFF5
- Protein
- Isoform 2 of FAD synthase
- EC
- 2.7.7.2
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 21 · 2 records with a druggable one
Structures
3 records of Q8NFF5 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8ROM | Crystal structure of human FAD synthase PAPS domain in complex with FAD | x-ray diffraction | A | FAD, PO4 | 1 (best 0.69) |
| 8RON | Crystal structure of human FAD synthase, isoform 2 | x-ray diffraction | A, B, C, D | — | 20 (best 0.81) |
| Q8NFF5 | AlphaFold monomer V2.0 prediction for FAD synthase (Q8NFF5) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8ROM chain A against the predicted model Q8NFF5: TM-score 0.97, RMSD 1.24 Å
- 8RON chain A against the predicted model Q8NFF5: TM-score 0.85, RMSD 3.38 Å
- 8RON chain D against the predicted model Q8NFF5: TM-score 0.82, RMSD 3.67 Å
- 8RON chain C against the predicted model Q8NFF5: TM-score 0.82, RMSD 3.76 Å
- 8RON chain B against the predicted model Q8NFF5: TM-score 0.80, RMSD 3.94 Å
Elsewhere
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