UniProt Q8NDL9
Cytosolic carboxypeptidase-like protein 5 (Q8NDL9)
Cytosolic carboxypeptidase-like protein 5 (UniProt Q8NDL9), EC 3.4.17.-, 3.4.17.24: 10 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 51 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8NDL9
- Protein
- Cytosolic carboxypeptidase-like protein 5
- EC
- 3.4.17.-, 3.4.17.24
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 51 · 8 records with a druggable one
Structures
11 records of Q8NDL9 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8V3M | CCP5 apo structure | x-ray diffraction | A | MLT, ZN | 6 (best 0.63) |
| 8V3N | CCP5 in complex with Glu-P-Glu transition state analog | x-ray diffraction | A | ZN, MLT, A1AAG | 4 (best 0.61) |
| 8V3O | CCP5 in complex with Glu-P-peptide 1 transition state analog | x-ray diffraction | A | ZN, MLT, K | 3 (best 0.50) |
| 8V3P | CCP5 in complex with Glu-P-peptide 2 transition state analog | x-ray diffraction | A | ZN | 2 (best 0.48) |
| 8V3Q | Structure of CCP5 class1 | electron microscopy | A | ZN, GLU | 6 (best 0.53) |
| 8V3R | Structure of CCP5 class2 | electron microscopy | A | ZN, GLU | 4 (best 0.53) |
| 8V3S | Structure of CCP5 class3 | electron microscopy | A | ZN, GLU | 3 (best 0.50) |
| 8V4K | CCP5 in complex with microtubules class1 | electron microscopy | E | ZN, GLU | 10 (best 0.79) |
| 8V4L | CCP5 in complex with microtubules class2 | electron microscopy | E | GLU, ZN | 7 (best 0.72) |
| 8V4M | CCP5 in complex with microtubules class3 | electron microscopy | E | GLU, ZN | 6 (best 0.76) |
| Q8NDL9 | AlphaFold monomer V2.0 prediction for cytosolic carboxypeptidase-like protein 5 (Q8NDL9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8V3R chain A against the predicted model Q8NDL9: TM-score 0.99, RMSD 0.80 Å
- 8V4L chain E against the predicted model Q8NDL9: TM-score 0.99, RMSD 0.83 Å
- 8V3S chain A against the predicted model Q8NDL9: TM-score 0.99, RMSD 0.83 Å
- 8V4M chain E against the predicted model Q8NDL9: TM-score 0.99, RMSD 0.84 Å
- 8V3Q chain A against the predicted model Q8NDL9: TM-score 0.99, RMSD 0.87 Å
- 8V4K chain E against the predicted model Q8NDL9: TM-score 0.99, RMSD 0.90 Å
- 8V3N chain A against the predicted model Q8NDL9: TM-score 0.98, RMSD 1.24 Å
- 8V3M chain A against the predicted model Q8NDL9: TM-score 0.97, RMSD 1.43 Å
- 8V3P chain A against the predicted model Q8NDL9: TM-score 0.97, RMSD 1.32 Å
- 8V3O chain A against the predicted model Q8NDL9: TM-score 0.97, RMSD 1.55 Å
Elsewhere
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