UniProt Q8NAT1
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (Q8NAT1)
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 (UniProt Q8NAT1), EC 2.4.1.312: 5 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 30 pockets. Binding sites, druggability and…
- UniProt
- Q8NAT1
- Protein
- Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
- EC
- 2.4.1.312
- Experimental structures
- 5
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 30 · 3 records with a druggable one
Structures
6 records of Q8NAT1 in the MolNFT archive: 5 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6XFI | Crystal Structures of beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2): Structural Basis for… | x-ray diffraction | A | UDP, NAG, PO4 | 4 (best 0.69) |
| 6XFI | Crystal structures of beta-1,4-N-acetylglucosaminyltransferase 2 (POMGNT2): structural basis for… | x-ray diffraction | A | UDP, NAG, PO4 | — |
| 6XI2 | Apo form of POMGNT2 | x-ray diffraction | A, B, D, C | NAG, PO4 | — |
| 6XI2 | Apo form of POMGNT2 | x-ray diffraction | A, B, D, C | NAG, PO4 | — |
| 8KB7 | Crystal structure of UDP/mannose-bound AGO61/beta-1,4-N-Acetylglucosaminyltransferase 2 (POMGNT2) | x-ray diffraction | A, B, C, D | UDP, NAG, MAN, CL | 20 (best 0.72) |
| Q8NAT1 | AlphaFold monomer V2.0 prediction for protein O-linked-mannose… | predicted | A | — | 6 (best 0.72) |
Ligands
Experiment against prediction
- 6XFI chain A against the predicted model Q8NAT1: TM-score 0.97, RMSD 1.53 Å
- 6XFI chain A against the predicted model Q8NAT1: TM-score 0.97, RMSD 1.53 Å
- 8KB7 chain C against the predicted model Q8NAT1: TM-score 0.94, RMSD 2.00 Å
- 6XI2 chain C against the predicted model Q8NAT1: TM-score 0.94, RMSD 2.21 Å
- 6XI2 chain C against the predicted model Q8NAT1: TM-score 0.94, RMSD 2.21 Å
- 8KB7 chain B against the predicted model Q8NAT1: TM-score 0.93, RMSD 2.18 Å
- 8KB7 chain D against the predicted model Q8NAT1: TM-score 0.93, RMSD 2.40 Å
- 8KB7 chain A against the predicted model Q8NAT1: TM-score 0.92, RMSD 2.46 Å
- 6XI2 chain A against the predicted model Q8NAT1: TM-score 0.92, RMSD 2.59 Å
- 6XI2 chain A against the predicted model Q8NAT1: TM-score 0.92, RMSD 2.59 Å
Elsewhere
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