UniProt Q8N766
ER membrane protein complex subunit 1 (Q8N766)
ER membrane protein complex subunit 1 (UniProt Q8N766): 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 80 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N766
- Protein
- ER membrane protein complex subunit 1
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 80 · 8 records with a druggable one
Structures
14 records of Q8N766 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WW7 | Structure of the human ER membrane protein complex in a lipid nanodisc | electron microscopy | A | NAG | 10 (best 0.79) |
| 6WW7 | Structure of the human er membrane protein complex in a lipid nanodisc | electron microscopy | A | NAG | — |
| 6Z3W | Human ER membrane protein complex | electron microscopy | A | — | — |
| 6Z3W | Human er membrane protein complex | electron microscopy | A | — | — |
| 7ADO | Cryo-EM structure of human ER membrane protein complex in lipid nanodiscs | electron microscopy | A | NAG, PCW | 10 (best 0.79) |
| 7ADO | Cryo-EM structure of human er membrane protein complex in lipid nanodiscs | electron microscopy | A | NAG, PCW | — |
| 7ADP | Cryo-EM structure of human ER membrane protein complex in GDN detergent | electron microscopy | A | NAG | 8 (best 0.80) |
| 7ADP | Cryo-EM structure of human er membrane protein complex in gdn detergent | electron microscopy | A | NAG | — |
| 8EOI | Structure of a human EMC:human Cav1.2 channel complex in GDN detergent | electron microscopy | A | NAG | 7 (best 0.79) |
| 8J0N | cryo-EM structure of human EMC | electron microscopy | A | NAG | 12 (best 0.84) |
| 8J0O | cryo-EM structure of human EMC and VDAC | electron microscopy | A | NAG | 10 (best 0.80) |
| 8S9S | Structure of the human ER membrane protein complex (EMC) in GDN | electron microscopy | 1 | NAG, PCW | 13 (best 0.79) |
| 9C7V | Structure of the human BOS:human EMC complex in GDN | electron microscopy | 1 | NAG | 10 (best 0.75) |
| Q8N766 | AlphaFold monomer V2.0 prediction for er membrane protein complex subunit 1 (Q8N766) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6WW7 chain A against the predicted model Q8N766: TM-score 0.97, RMSD 2.11 Å
- 6WW7 chain A against the predicted model Q8N766: TM-score 0.97, RMSD 2.11 Å
- 8S9S chain 1 against the predicted model Q8N766: TM-score 0.97, RMSD 2.06 Å
- 9C7V chain 1 against the predicted model Q8N766: TM-score 0.97, RMSD 2.06 Å
- 7ADO chain A against the predicted model Q8N766: TM-score 0.96, RMSD 2.25 Å
- 7ADO chain A against the predicted model Q8N766: TM-score 0.96, RMSD 2.25 Å
- 7ADP chain A against the predicted model Q8N766: TM-score 0.94, RMSD 2.58 Å
- 7ADP chain A against the predicted model Q8N766: TM-score 0.94, RMSD 2.58 Å
- 8EOI chain A against the predicted model Q8N766: TM-score 0.94, RMSD 2.72 Å
- 8J0O chain A against the predicted model Q8N766: TM-score 0.94, RMSD 2.93 Å
Elsewhere
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