UniProt Q8N6U8
G-protein coupled receptor 161 (Q8N6U8)
G-protein coupled receptor 161 (UniProt Q8N6U8): 2 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N6U8
- Protein
- G-protein coupled receptor 161
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 12 · 3 records with a druggable one
Structures
3 records of Q8N6U8 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8KH4 | Cryo-EM structure of the GPR161-Gs complex | electron microscopy | A | CLR | 3 (best 0.73) |
| 8SMV | GPR161 Gs heterotrimer | electron microscopy | R | CLR | 4 (best 0.75) |
| Q8N6U8 | AlphaFold monomer V2.0 prediction for G-protein coupled receptor 161 (Q8N6U8) | predicted | A | — | 5 (best 0.73) |
Ligands
- CLR · Cholesterol · in 2 records
Experiment against prediction
- 8KH4 chain A against the predicted model Q8N6U8: TM-score 0.95, RMSD 1.47 Å
- 8SMV chain R against the predicted model Q8N6U8: TM-score 0.95, RMSD 1.52 Å
Elsewhere
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