UniProt Q8N5Y8
Mono [ADP-ribose] polymerase PARP16 (Q8N5Y8)
Mono [ADP-ribose] polymerase PARP16 (UniProt Q8N5Y8), EC 2.4.2.-, 2.4.2.30: 9 experimental structures on GenesisL1, 5 ligands bound, 22 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q8N5Y8
- Protein
- Mono [ADP-ribose] polymerase PARP16
- EC
- 2.4.2.-, 2.4.2.30
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 22 · 2 records with a druggable one
Structures
9 records of Q8N5Y8 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4F0D | Human ARTD15/PARP16 IN COMPLEX WITH 3-AMINOBENZAMIDE | x-ray diffraction | A, B | — | — |
| 4F0D | Human ARTD15/PARP16 in complex with 3-aminobenzamide | x-ray diffraction | A, B | — | — |
| 6HXR | Human PARP16 (ARTD15) IN COMPLEX WITH EB-47 | x-ray diffraction | A, B, C | UHB | — |
| 6HXR | Human PARP16 (ARTD15) in complex with eb-47 | x-ray diffraction | A, B, C | UHB | — |
| 6HXS | Human PARP16 (ARTD15) IN COMPLEX WITH CARBA-NAD | x-ray diffraction | A, B, C | CNA, SO4, ADN | 11 (best 0.75) |
| 6HXS | Human PARP16 (ARTD15) in complex with carba-NAD | x-ray diffraction | A, B, C | CNA, SO4, ADN | — |
| 6W65 | Human PARP16 in complex with RBN010860 | x-ray diffraction | A, B, C | T9D | 11 (best 0.76) |
| 6W65 | Human PARP16 in complex with RBN010860 | x-ray diffraction | A, B, C | T9D | — |
| Q8N5Y8 | AlphaFold monomer V2.0 prediction for protein mono-ADP- ribosyltransferase PARP16 (Q8N5Y8) | — | — | — |
Ligands
- ADN · Adenosine · in 2 records
- CNA · Carba-nicotinamide-adenine-dinucleotide · in 2 records
- SO4 · Sulfate ion · in 2 records
- T9D · 5-{5-[(piperidin-4-yl)oxy]-2H-isoindol-2-yl}-4-(trifluoromethyl)pyridazin-3(2H)-one · in 2 records
- UHB · 2-[4-[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]carbonylpiperazin-1-yl]-N-(1-oxidanylidene-2,3-dihydroisoindol-4-yl)ethanamide · in 2 records
Elsewhere
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