UniProt Q8N3U4
Cohesin subunit SA-2 (Q8N3U4)
Cohesin subunit SA-2 (UniProt Q8N3U4): 10 experimental structures and 1 predicted model on GenesisL1, 55 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N3U4
- Protein
- Cohesin subunit SA-2
- Experimental structures
- 10
- Predicted models
- 1
- Pockets
- 55 · 4 records with a druggable one
Structures
11 records of Q8N3U4 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4PJU | crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion… | x-ray diffraction | A | — | — |
| 4PJU | Crystal structure of human stromal antigen 2 (SA2) in complex with sister chromatid cohesion… | x-ray diffraction | A | — | — |
| 4PJW | crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion… | x-ray diffraction | A | — | — |
| 4PJW | Crystal structure of human stromal antigen 2 (SA2) in complex with sister chromatid cohesion… | x-ray diffraction | A | — | — |
| 4PK7 | crystal structure of human Stromal Antigen 2 (SA2) in complex with Sister Chromatid Cohesion… | x-ray diffraction | A | — | — |
| 4PK7 | Crystal structure of human stromal antigen 2 (SA2) in complex with sister chromatid cohesion… | x-ray diffraction | A | — | — |
| 6QNX | Structure of the SA2/SCC1/CTCF complex | x-ray diffraction | A | — | 10 (best 0.75) |
| 6QNX | Structure of the SA2/SCC1/CTCF complex | x-ray diffraction | A | — | — |
| 7ZJS | Structural basis of centromeric cohesion protection by SGO1 | x-ray diffraction | A, C | — | 20 (best 0.78) |
| 8K4D | Structure of the SA2/Scc1/CENP_U complex | x-ray diffraction | A | — | 11 (best 0.74) |
| Q8N3U4 | AlphaFold monomer V2.0 prediction for cohesin subunit sa-2 (Q8N3U4) | predicted | A | — | 14 (best 0.77) |
Experiment against prediction
- 4PK7 chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 0.82 Å
- 4PK7 chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 0.82 Å
- 4PJU chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 0.83 Å
- 4PJU chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 0.83 Å
- 4PJW chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 0.86 Å
- 4PJW chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 0.86 Å
- 8K4D chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 1.10 Å
- 6QNX chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 1.17 Å
- 6QNX chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 1.17 Å
- 7ZJS chain A against the predicted model Q8N3U4: TM-score 0.99, RMSD 1.19 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.