UniProt Q8N0S6
Centromere protein L (Q8N0S6)
Centromere protein L (UniProt Q8N0S6): 14 experimental structures and 1 predicted model on GenesisL1, 35 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8N0S6
- Protein
- Centromere protein L
- Experimental structures
- 14
- Predicted models
- 1
- Pockets
- 35 · 7 records with a druggable one
Structures
15 records of Q8N0S6 in the MolNFT archive: 14 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7PKN | Structure of the human CCAN deltaCT complex | electron microscopy | L | — | 4 (best 0.84) |
| 7PKN | Structure of the human ccan deltact complex | electron microscopy | L | — | — |
| 7QOO | Structure of the human inner kinetochore CCAN complex | electron microscopy | L | — | 4 (best 0.80) |
| 7QOO | Structure of the human inner kinetochore ccan complex | electron microscopy | L | — | — |
| 7R5S | Structure of the human CCAN bound to alpha satellite DNA | electron microscopy | L | — | 6 (best 0.86) |
| 7R5S | Structure of the human ccan bound to alpha satellite DNA | electron microscopy | L | — | — |
| 7R5V | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | L | — | 3 (best 0.85) |
| 7R5V | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | L | — | — |
| 7XHN | Structure of human inner kinetochore CCAN-DNA complex | electron microscopy | L | — | 8 (best 0.80) |
| 7XHO | Structure of human inner kinetochore CCAN complex | electron microscopy | L | — | 6 (best 0.80) |
| 7YWX | Structure of the human CCAN CENP-A alpha-satellite complex | electron microscopy | L | — | — |
| 7YWX | Structure of the human ccan cenp-a alpha-satellite complex | electron microscopy | L | — | — |
| 7YYH | Structure of the human CCANdeltaT CENP-A alpha-satellite complex | electron microscopy | L | — | 4 (best 0.86) |
| 7YYH | Structure of the human ccandeltat cenp-a alpha-satellite complex | electron microscopy | L | — | — |
| Q8N0S6 | AlphaFold monomer V2.0 prediction for centromere protein L (Q8N0S6) | predicted | A | — | — |
Experiment against prediction
- 7YYH chain L against the predicted model Q8N0S6: TM-score 0.95, RMSD 1.79 Å
- 7YYH chain L against the predicted model Q8N0S6: TM-score 0.95, RMSD 1.79 Å
- 7R5V chain L against the predicted model Q8N0S6: TM-score 0.95, RMSD 1.79 Å
- 7R5V chain L against the predicted model Q8N0S6: TM-score 0.95, RMSD 1.79 Å
- 7XHO chain L against the predicted model Q8N0S6: TM-score 0.94, RMSD 1.99 Å
- 7XHN chain L against the predicted model Q8N0S6: TM-score 0.94, RMSD 1.96 Å
- 7QOO chain L against the predicted model Q8N0S6: TM-score 0.94, RMSD 1.96 Å
- 7QOO chain L against the predicted model Q8N0S6: TM-score 0.94, RMSD 1.96 Å
- 7PKN chain L against the predicted model Q8N0S6: TM-score 0.94, RMSD 2.08 Å
- 7PKN chain L against the predicted model Q8N0S6: TM-score 0.94, RMSD 2.08 Å
Elsewhere
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