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UniProt Q8K1F4

5-hydroxytryptamine receptor 3A (Q8K1F4)

5-hydroxytryptamine receptor 3A (UniProt Q8K1F4): 7 experimental structures on GenesisL1, 4 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8K1F4
Protein
5-hydroxytryptamine receptor 3A
Experimental structures
7
Predicted models
0
Ligands
4
Pockets
60 · 3 records with a druggable one

Structures

7 records of Q8K1F4 in the MolNFT archive: 7 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6W1JCryo-EM structure of 5HT3A receptor in presence of Alosetronelectron microscopyA, B, C, D, ENAG, S7Y20 (best 0.84)
6W1JCryo-EM structure of 5HT3A receptor in presence of alosetronelectron microscopyA, B, C, D, ENAG, S7Y—
6W1MCryo-EM structure of 5HT3A receptor in presence of Ondansetronelectron microscopyA, B, C, D, ENAG, S8720 (best 0.86)
6W1MCryo-EM structure of 5HT3A receptor in presence of ondansetronelectron microscopyA, B, C, D, ENAG, S87—
6W1YCryo-EM structure of 5HT3A receptor in presence of Palonosetronelectron microscopyA, B, C, D, ENAG, O7B20 (best 0.86)
6W1YCryo-EM structure of 5HT3A receptor in presence of palonosetronelectron microscopyA, B, C, D, ENAG, O7B—
6Y1ZMouse serotonin 5HT3 receptor in complex with palonosetronelectron microscopyA, D, B, C, ENAG, O7B—

Ligands

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 7 records
  • O7B · (3~{a}~{S})-2-[(3~{S})-1-azabicyclo[2.2.2]octan-3-yl]-3~{a},4,5,6-tetrahydro-3~{H}-benzo[de]isoquinolin-1-one · in 3 records
  • S7Y · alosetron · in 2 records
  • S87 · ondansetron · in 2 records

Elsewhere

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