UniProt Q8IXK2
Polypeptide N-acetylgalactosaminyltransferase 12 (Q8IXK2)
Polypeptide N-acetylgalactosaminyltransferase 12 (UniProt Q8IXK2), EC 2.4.1.41: 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 17 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8IXK2
- Protein
- Polypeptide N-acetylgalactosaminyltransferase 12
- EC
- 2.4.1.41
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 17 · 1 record with a druggable one
Structures
3 records of Q8IXK2 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6PXU | Crystal structure of human GalNAc-T12 bound to a diglycosylated peptide, Mn2+, and UDP | x-ray diffraction | A, B | UDP, MN, A2G | 17 (best 0.80) |
| 6PXU | Crystal structure of human galnac-T12 bound to a diglycosylated peptide, MN2+, and udp | x-ray diffraction | A, B | UDP, MN, A2G | — |
| Q8IXK2 | AlphaFold monomer V2.0 prediction for polypeptide N-acetylgalactosaminyltransferase 12 (Q8IXK2) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6PXU chain A against the predicted model Q8IXK2: TM-score 1.00, RMSD 0.38 Å
- 6PXU chain A against the predicted model Q8IXK2: TM-score 1.00, RMSD 0.38 Å
- 6PXU chain B against the predicted model Q8IXK2: TM-score 1.00, RMSD 0.53 Å
- 6PXU chain B against the predicted model Q8IXK2: TM-score 1.00, RMSD 0.53 Å
Elsewhere
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