UniProt Q8IXI1
Mitochondrial Rho GTPase 2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (UniProt Q8IXI1), EC 3.6.5.-: 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 17 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IXI1
- Protein
- Mitochondrial Rho GTPase 2
- EC
- 3.6.5.-
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 17 · 2 records with a druggable one
Structures
3 records of Q8IXI1 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KUT | hMiro2 C-terminal GTPase domain, GDP-bound | x-ray diffraction | A, B, C | GDP, MG | 5 (best 0.81) |
| 5KUT | HMIRO2 C-terminal GTPase domain, GDP-bound | x-ray diffraction | A, B, C | GDP, MG | — |
| Q8IXI1 | AlphaFold monomer V2.0 prediction for mitochondrial rho GTPase 2 (Q8IXI1) | predicted | A | — | 12 (best 0.56) |
Ligands
Experiment against prediction
- 5KUT chain C against the predicted model Q8IXI1: TM-score 0.91, RMSD 1.82 Å
- 5KUT chain C against the predicted model Q8IXI1: TM-score 0.91, RMSD 1.82 Å
- 5KUT chain B against the predicted model Q8IXI1: TM-score 0.89, RMSD 1.83 Å
- 5KUT chain B against the predicted model Q8IXI1: TM-score 0.89, RMSD 1.83 Å
- 5KUT chain A against the predicted model Q8IXI1: TM-score 0.89, RMSD 1.99 Å
- 5KUT chain A against the predicted model Q8IXI1: TM-score 0.89, RMSD 1.99 Å
Elsewhere
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