UniProt Q8IUC6
Tir domain-containing adapter molecule 1 (Q8IUC6)
Tir domain-containing adapter molecule 1 (UniProt Q8IUC6): 8 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8IUC6
- Protein
- Tir domain-containing adapter molecule 1
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
9 records of Q8IUC6 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2M1X | TICAM-1 TIR domain structure | solution nmr | A | — | — |
| 2M1X | Ticam-1 tir domain structure | solution nmr | A | — | — |
| 2M63 | The protease-resistant N-terminal domain of TIR-domain containing adaptor molecule-1, TICAM-1 | solution nmr | A | — | — |
| 2M63 | The protease-resistant N-terminal domain of tir-domain containing adaptor molecule-1, ticam-1 | solution nmr | A | — | — |
| 4BSX | Crystal Structure of the N terminal domain of TRIF (TIR-domain- containing adapter-inducing… | x-ray diffraction | A, B, C, D | — | — |
| 4BSX | Crystal structure of the N terminal domain of trif (tir- domain-containing adapter-inducing… | x-ray diffraction | A, B, C, D | — | — |
| 4C0M | Crystal Structure of the N terminal domain of wild type TRIF (TIR- domain-containing… | x-ray diffraction | A, B, C, D | — | — |
| 4C0M | Crystal structure of the N terminal domain of wild type trif (tir-domain-containing… | x-ray diffraction | A, B, C, D | — | — |
| Q8IUC6 | AlphaFold monomer V2.0 prediction for tir domain-containing adapter molecule 1 (Q8IUC6) | predicted | A | — | 3 (best 0.41) |
Experiment against prediction
- 4BSX chain B against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.53 Å
- 4BSX chain B against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.53 Å
- 4BSX chain A against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.54 Å
- 4BSX chain A against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.54 Å
- 4C0M chain B against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.54 Å
- 4C0M chain B against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.54 Å
- 4C0M chain A against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.55 Å
- 4C0M chain A against the predicted model Q8IUC6: TM-score 0.99, RMSD 0.55 Å
- 2M63 chain A against the predicted model Q8IUC6: TM-score 0.88, RMSD 1.78 Å
- 2M63 chain A against the predicted model Q8IUC6: TM-score 0.88, RMSD 1.78 Å
Elsewhere
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