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UniProt Q8GKX2

Class B metallo-beta-lactamase (Q8GKX2)

Class B metallo-beta-lactamase (UniProt Q8GKX2): 6 experimental structures on GenesisL1, 4 ligands bound, 9 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8GKX2
Protein
Class B metallo-beta-lactamase
Experimental structures
6
Predicted models
0
Ligands
4
Pockets
9 · 3 records with a druggable one

Structures

6 records of Q8GKX2 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
5N55mono-Zinc VIM-5 metallo-beta-lactamase in complex with…x-ray diffractionA, B, CZN, 8NN3 (best 0.78)
5N55Mono-zinc vim-5 metallo-beta-lactamase in complex with (1-chloro-4…x-ray diffractionA, B, CZN, 8NN—
5N58di-Zinc VIM-5 metallo-beta-lactamase in complex with…x-ray diffractionA, BZN, 93W5 (best 0.59)
5N58Di-zinc vim-5 metallo-beta-lactamase in complex with (1-chloro-4…x-ray diffractionA, BZN, 93W—
5NAImono-Zinc VIM-5 metallo-beta-lactamase in complex with…x-ray diffractionAZN, 93W, F1 (best 0.50)
5NAIMono-zinc vim-5 metallo-beta-lactamase in complex with (1-chloro-4…x-ray diffractionAZN, 93W, F—

Ligands

  • ZN · Zinc ion · in 6 records
  • 93W · (2~{R})-2-[(1-chloranyl-4-oxidanyl-isoquinolin-3-yl) carbonylamino]-3-(1~{H}-indol-3-yl)propanoic acid · in 4 records
  • 8NN · (1-chloro-4-hydroxyisoquinoline-3-carbonyl)-L-tryptophan · in 2 records
  • F · Fluoride ion · in 2 records

Elsewhere

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