UniProt Q8GBW6
Methylmalonyl-CoA carboxyltransferase 12S subunit (Q8GBW6)
Methylmalonyl-CoA carboxyltransferase 12S subunit (UniProt Q8GBW6), EC 2.1.3.1: 4 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 40 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8GBW6
- Protein
- Methylmalonyl-CoA carboxyltransferase 12S subunit
- EC
- 2.1.3.1
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 40 · 2 records with a druggable one
Structures
5 records of Q8GBW6 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1ON3 | Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme… | x-ray diffraction | A, B, C, D, E, F | CD, MCA, DXX | 20 (best 0.81) |
| 1ON3 | Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 1ON9 | Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme… | x-ray diffraction | A, B, C, D, E, F | CD, MCA | 20 (best 0.82) |
| 1ON9 | Transcarboxylase 12S crystal structure: hexamer assembly and substrate binding to a multienzyme… | x-ray diffraction | A, B, C, D, E, F | — | — |
| Q8GBW6 | AlphaFold monomer V2.0 prediction for methylmalonyl-CoA carboxyltransferase 12S subunit (Q8GBW6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 1ON3 chain B against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.42 Å
- 1ON3 chain B against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.42 Å
- 1ON3 chain C against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.45 Å
- 1ON3 chain C against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.45 Å
- 1ON3 chain F against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.48 Å
- 1ON3 chain F against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.48 Å
- 1ON9 chain B against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.49 Å
- 1ON9 chain B against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.49 Å
- 1ON3 chain A against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.49 Å
- 1ON3 chain A against the predicted model Q8GBW6: TM-score 1.00, RMSD 0.49 Å
Elsewhere
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