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Ligand · DXX

DXX · Methylmalonic acid

DXX, Methylmalonic acid (C4 H6 O4, 118.1 g/mol), in the MolNFT structures on GenesisL1: bound in 5 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
DXX
Formula
C4 H6 O4
Class
ligand
Structures
5
PDB entries
4

Binding sites

DXX in 5 structures; the first of them:

  • 5G1W · Apo Structure of Linalool Dehydratase-Isomerase · DXX A1370 · binds ARG155, TYR191, HIS195, THR197
  • 7AGS · Structure of the AcylTransferase domain of Mycocerosic Acid Synthase from Mycobacterium… · DXX A901 · binds GLY539, GLN540, GLN594, SER623, MET624, ARG648, SER726, HIS727 and 1 more
  • 6L3N · Crystal structure of the acyltransferase domain from the third module of the ansamitocin… · DXX A501 · binds GLN98, GLN152, SER180, GLN181, ARG205, ILE209, MET219, PHE282 and 2 more
  • 7AGS · Structure of the acyltransferase domain of mycocerosic acid synthase from mycobacterium… · DXX A901 · binds GLY539, GLN540, GLN594, SER623, MET624, ARG648, SER726, HIS727 and 1 more
  • 7AGU · Structure of the S726F mutant of acyltransferase domain of mycocerosic acid synthase from… · DXX A901 · binds GLY539, GLN540, GLN594, SER623, MET624, ARG648, PHE726, HIS727

Residues it binds most

GLN 7, ARG 9, HIS 9, SER 7, LEU 6, MET 5, PHE 5, ILE 4, GLY 3, THR 2 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • PO4 · Phosphate ion
  • GOL · Glycerol

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