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UniProt Q8CZR7

7,8-dihydroneopterin aldolase (Q8CZR7)

7,8-dihydroneopterin aldolase (UniProt Q8CZR7), EC 4.1.2.25: 5 experimental structures on GenesisL1, 4 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q8CZR7
Protein
7,8-dihydroneopterin aldolase
EC
4.1.2.25
Experimental structures
5
Predicted models
0
Ligands
4
Pockets
18 · 4 records with a druggable one

Structures

5 records of Q8CZR7 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6OJODihydroneopterin aldolase (dhna) from yersinia pestis co-crystallized with pterinex-ray diffractionA, B, C, DPE0—
7SU4Dihydroneopterin aldolase (DHNA) Tyr53Phe from Yersinia pestis co-crystallized with…x-ray diffractionA, B, C, DNPR5 (best 0.55)
7SU6DIHYDRONEOPTERIN ALDOLASE (DHNA) Lys98Ala FROM YERSINIA PESTIS CO-CRYSTALLIZED with…x-ray diffractionA, B, C, DNPR6 (best 0.55)
7SU7Dihydroneopterin aldolase (DHNA) from Yersinia pestis co-crystallized with productx-ray diffractionA, B, C, DPH26 (best 0.51)
7SU8DIHYDRONEOPTERIN ALDOLASE (DHNA) FROM YERSINIA PESTIS with alkylated Cys50 CO-CRYSTALLIZED with…x-ray diffractionA, BNEN, PH21 (best 0.53)

Ligands

  • NPR · 2-amino-7,8-dihydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone · in 2 records
  • PH2 · 2-amino-6-hydroxymethyl-7,8-dihydro-3H-pteridin-4-one · in 2 records
  • NEN · 1-ethyl-pyrrolidine-2,5-dione · in 1 record
  • PE0 · Pterine · in 1 record

Elsewhere

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