GL1X · GenesisL1 explorer

Ligand · NPR

NPR · 2-amino-7,8-dihydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone

NPR, 2-amino-7,8-dihydro-6-(1,2,3-trihydroxypropyl)-4(1H)-pteridinone (C9 H13 N5 O4, 255.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues…

Component
NPR
Formula
C9 H13 N5 O4
Class
ligand
Structures
4
PDB entries
4

Binding sites

NPR in 4 structures; the first of them:

  • 7SU4 · Dihydroneopterin aldolase (DHNA) Tyr53Phe from Yersinia pestis co-crystallized with… · NPR A201 · binds GLY16, VAL17, TYR18, GLU21, ALA70, LEU71, VAL72, GLU73 and 9 more
  • 7SU6 · DIHYDRONEOPTERIN ALDOLASE (DHNA) Lys98Ala FROM YERSINIA PESTIS CO-CRYSTALLIZED with… · NPR A201 · binds VAL4, CYS50, LEU51, SER52, TYR53, ALA54, GLY16, VAL17 and 6 more
  • 7WII · The THF-II riboswitch bound to NPR · NPR V101 · binds U17, A21, C22, G25, A41, A42, C43, U44 and 1 more
  • 8XZM · Crystal structure of folE riboswitch with DHN · NPR A106 · binds U13, U14, A17, C18, G21, C40, U41, A42

Residues it binds most

ALA 8, VAL 8, LEU 8, GLU 8, CYS 8, SER 8, TYR 8, A 2, GLY 6, U 2 (residue and the binding sites it lines).

Found with

  • SPM · Spermine
  • MG · Magnesium ion
  • GOL · Glycerol
  • MPD · (4S)-2-methyl-2,4-pentanediol
  • TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.