UniProt Q8C0L6
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (Q8C0L6)
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase (UniProt Q8C0L6), EC 1.5.3.13: 8 experimental structures and 1 predicted model on GenesisL1, 5 ligands bound, 10 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q8C0L6
- Protein
- Peroxisomal N(1)-acetyl-spermine/spermidine oxidase
- EC
- 1.5.3.13
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 5
- Pockets
- 10 · 4 records with a druggable one
Structures
9 records of Q8C0L6 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5LAE | Crystal structure of murine N1-acetylpolyamine oxidase | x-ray diffraction | A | FAD | 3 (best 0.81) |
| 5LAE | Crystal structure of murine N1-acetylpolyamine oxidase | x-ray diffraction | A | FAD | — |
| 5LFO | Crystal structure of murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | x-ray diffraction | A | FAD, SP5 | 2 (best 0.81) |
| 5LFO | Crystal structure of murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | x-ray diffraction | A | FAD, SP5 | — |
| 5LGB | Crystal structure of murine N1-acetylpolyamine oxidase in complex with MDL72527 | x-ray diffraction | A | 6YU, MD2 | — |
| 5LGB | Crystal structure of murine N1-acetylpolyamine oxidase in complex with MDL72527 | x-ray diffraction | A | 6YU, MD2 | — |
| 5MBX | Crystal structure of reduced murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | x-ray diffraction | A | FAD, SP5, SO4 | 2 (best 0.81) |
| 5MBX | Crystal structure of reduced murine N1-acetylpolyamine oxidase in complex with N1-acetylspermine | x-ray diffraction | A | FAD, SP5, SO4 | — |
| Q8C0L6 | AlphaFold monomer V2.0 prediction for peroxisomal N(1)-acetyl- SPERMINE/SPERMIDINE oxidase (Q8C0L6) | predicted | A | — | 3 (best 0.85) |
Ligands
Experiment against prediction
- 5MBX chain A against the predicted model Q8C0L6: TM-score 1.00, RMSD 0.42 Å
- 5MBX chain A against the predicted model Q8C0L6: TM-score 1.00, RMSD 0.42 Å
- 5LGB chain A against the predicted model Q8C0L6: TM-score 1.00, RMSD 0.49 Å
- 5LGB chain A against the predicted model Q8C0L6: TM-score 1.00, RMSD 0.49 Å
- 5LFO chain A against the predicted model Q8C0L6: TM-score 1.00, RMSD 0.49 Å
- 5LFO chain A against the predicted model Q8C0L6: TM-score 1.00, RMSD 0.49 Å
- 5LAE chain A against the predicted model Q8C0L6: TM-score 0.99, RMSD 0.59 Å
- 5LAE chain A against the predicted model Q8C0L6: TM-score 0.99, RMSD 0.59 Å
Elsewhere
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