UniProt Q8C0D4
Rho GTPase-activating protein 12 (Q8C0D4)
Rho GTPase-activating protein 12 (UniProt Q8C0D4): 2 experimental structures and 1 predicted model on GenesisL1, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q8C0D4
- Protein
- Rho GTPase-activating protein 12
- Experimental structures
- 2
- Predicted models
- 1
- Pockets
- 3 · 0 records with a druggable one
Structures
3 records of Q8C0D4 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GVC | Structure of ArhGAP12 bound to G-Actin | x-ray diffraction | R, Q, S, T | — | — |
| 6GVC | Structure of ARHGAP12 bound to G-actin | x-ray diffraction | R, Q, S, T | — | — |
| Q8C0D4 | AlphaFold monomer V2.0 prediction for rho GTPase-activating protein 12 (Q8C0D4) | predicted | A | — | 3 (best 0.49) |
Experiment against prediction
- 6GVC chain R against the predicted model Q8C0D4: TM-score 0.98, RMSD 0.75 Å
- 6GVC chain R against the predicted model Q8C0D4: TM-score 0.98, RMSD 0.75 Å
- 6GVC chain S against the predicted model Q8C0D4: TM-score 0.98, RMSD 0.78 Å
- 6GVC chain S against the predicted model Q8C0D4: TM-score 0.98, RMSD 0.78 Å
- 6GVC chain T against the predicted model Q8C0D4: TM-score 0.97, RMSD 1.43 Å
- 6GVC chain T against the predicted model Q8C0D4: TM-score 0.97, RMSD 1.43 Å
- 6GVC chain Q against the predicted model Q8C0D4: TM-score 0.97, RMSD 1.46 Å
- 6GVC chain Q against the predicted model Q8C0D4: TM-score 0.97, RMSD 1.46 Å
Elsewhere
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