UniProt Q8BLU0
Leucine-rich repeat transmembrane protein FLRT2 (Q8BLU0)
Leucine-rich repeat transmembrane protein FLRT2 (UniProt Q8BLU0): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- Q8BLU0
- Protein
- Leucine-rich repeat transmembrane protein FLRT2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 14 · 1 record with a druggable one
Structures
9 records of Q8BLU0 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V2C | mouse FLRT2 LRR domain in complex with rat Unc5D Ig1 domain | x-ray diffraction | A, C | — | — |
| 4V2C | Mouse FLRT2 lrr domain in complex with rat UNC5D IG1 domain | x-ray diffraction | A, C | — | — |
| 4V2D | FLRT2 LRR domain | x-ray diffraction | A | — | — |
| 4V2D | FLRT2 lrr domain | x-ray diffraction | A | — | — |
| 5FTT | Octameric complex of Latrophilin 3 (Lec, Olf) , Unc5D (Ig, Ig2, TSP1) and FLRT2 (LRR) | x-ray diffraction | B, F | NAG | — |
| 5FTT | Octameric complex of latrophilin 3 (lec, olf) , UNC5D (ig, IG2, TSP1) and FLRT2 (lrr) | x-ray diffraction | B, F | — | — |
| 5FTU | Tetrameric complex of Latrophilin 3, Unc5D and FLRT2 | x-ray diffraction | B, F, J | NAG | 14 (best 0.81) |
| 5FTU | Tetrameric complex of latrophilin 3, UNC5D and FLRT2 | x-ray diffraction | B, F, J | — | — |
| Q8BLU0 | AlphaFold monomer V2.0 prediction for leucine-rich repeat transmembrane protein FLRT2 (Q8BLU0) | predicted | A | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 2 records
Experiment against prediction
- 4V2D chain A against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.67 Å
- 4V2D chain A against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.67 Å
- 4V2C chain C against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.67 Å
- 4V2C chain C against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.67 Å
- 4V2C chain A against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.67 Å
- 4V2C chain A against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.67 Å
- 5FTT chain B against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.82 Å
- 5FTT chain B against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.82 Å
- 5FTU chain F against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.86 Å
- 5FTU chain F against the predicted model Q8BLU0: TM-score 0.99, RMSD 0.86 Å
Elsewhere
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