UniProt Q8A2F6

Endo-4-O-sulfatase (Q8A2F6)

Endo-4-O-sulfatase (UniProt Q8A2F6), EC 3.1.6.-: 2 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q8A2F6
Protein: Endo-4-O-sulfatase
EC: 3.1.6.-
Experimental structures: 2
Predicted models: 1
Ligands: 4
Pockets: 8 · 1 record with a druggable one

Structures

3 records of Q8A2F6 in the MolNFT archive: 2 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
6S21	Metabolism of multiple glycosaminoglycans by bacteroides thetaiotaomicron is orchestrated by a…	x-ray diffraction	A, B, C	BDP, ASG, GCD, CA	8 (best 0.72)
6S21	Metabolism of multiple glycosaminoglycans by bacteroides thetaiotaomicron is orchestrated by a…	x-ray diffraction	A, B, C	BDP, ASG, GCD, CA	—
Q8A2F6	AlphaFold monomer V2.0 prediction for endo-4-O-sulfatase (Q8A2F6)	predicted	A	—	—

Ligands

ASG · 2-acetamido-2-deoxy-4-O-sulfo-beta-D-galactopyranose · in 2 records
BDP · beta-D-glucopyranuronic acid · in 2 records
CA · Calcium ion · in 2 records
GCD · 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid · in 2 records

Experiment against prediction

6S21 chain A against the predicted model Q8A2F6: TM-score 1.00, RMSD 0.41 Å
6S21 chain A against the predicted model Q8A2F6: TM-score 1.00, RMSD 0.41 Å
6S21 chain B against the predicted model Q8A2F6: TM-score 1.00, RMSD 0.43 Å
6S21 chain B against the predicted model Q8A2F6: TM-score 1.00, RMSD 0.43 Å
6S21 chain C against the predicted model Q8A2F6: TM-score 1.00, RMSD 0.46 Å
6S21 chain C against the predicted model Q8A2F6: TM-score 1.00, RMSD 0.46 Å

Elsewhere

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