UniProt Q86YT6
E3 ubiquitin-protein ligase MIB1 (Q86YT6)
E3 ubiquitin-protein ligase MIB1 (UniProt Q86YT6), EC 2.3.2.23, 2.3.2.24: 10 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q86YT6
- Protein
- E3 ubiquitin-protein ligase MIB1
- EC
- 2.3.2.23, 2.3.2.24, 2.3.2.27
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 11 · 3 records with a druggable one
Structures
11 records of Q86YT6 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4TSE | Crystal Structure of the Mib Repeat Domain of Mind bomb 1 | x-ray diffraction | A, B | — | — |
| 4TSE | Crystal structure of the mib repeat domain of mind bomb 1 | x-ray diffraction | A, B | — | — |
| 4XI6 | Crystal structure of the MZM-REP domains of Mind bomb 1 | x-ray diffraction | A | — | — |
| 4XI6 | Crystal structure of the mzm-rep domains of mind bomb 1 | x-ray diffraction | A | — | — |
| 4XI7 | Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with Jagged1 N-box peptide | x-ray diffraction | A | — | — |
| 4XI7 | Crystal structure of the mzm-rep domains of mind bomb 1 in complex with JAGGED1 N-box peptide | x-ray diffraction | A | — | — |
| 4XIB | Crystal structure of the MZM-REP domains of Mind bomb 1 in complex with fly Delta N-box peptide | x-ray diffraction | A | — | — |
| 4XIB | Crystal structure of the mzm-rep domains of mind bomb 1 in complex with fly delta N-box peptide | x-ray diffraction | A | — | — |
| 8V0D | Ubch5B-RING3 of MIB1 fusion structure | x-ray diffraction | B, A | ZN | 3 (best 0.58) |
| 8V0E | ANK repeat of MIB1 | x-ray diffraction | A, B | — | 1 (best 0.60) |
| Q86YT6 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase MIB1 (Q86YT6) | predicted | A | — | 7 (best 0.65) |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 8V0D chain A against the predicted model P62837: TM-score 0.69, RMSD 0.59 Å
- 8V0D chain B against the predicted model P62837: TM-score 0.68, RMSD 0.76 Å
- 8V0E chain B against the predicted model Q86YT6: TM-score 0.97, RMSD 1.24 Å
- 8V0E chain A against the predicted model Q86YT6: TM-score 0.97, RMSD 1.28 Å
- 4XI7 chain A against the predicted model Q86YT6: TM-score 0.81, RMSD 1.22 Å
- 4XI7 chain A against the predicted model Q86YT6: TM-score 0.81, RMSD 1.22 Å
- 4XIB chain A against the predicted model Q86YT6: TM-score 0.81, RMSD 1.24 Å
- 4XIB chain A against the predicted model Q86YT6: TM-score 0.81, RMSD 1.24 Å
- 4XI6 chain A against the predicted model Q86YT6: TM-score 0.81, RMSD 1.32 Å
- 4XI6 chain A against the predicted model Q86YT6: TM-score 0.81, RMSD 1.32 Å
Elsewhere
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