UniProt Q86VB7
Scavenger receptor cysteine-rich type 1 protein M130 (Q86VB7)
Scavenger receptor cysteine-rich type 1 protein M130 (UniProt Q86VB7): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 55 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q86VB7
- Protein
- Scavenger receptor cysteine-rich type 1 protein M130
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 55 · 4 records with a druggable one
Structures
5 records of Q86VB7 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8XMK | Local refinement of SRCR5-9 domains | electron microscopy | D, E, F | NAG, CA | 14 (best 0.61) |
| 8XMP | Structure of CD163 in complex with Hb-Hp | electron microscopy | E, F, D | NAG, CA | 15 (best 0.65) |
| 8XMW | Local refinement of Hb-Hp bind to CD163 | electron microscopy | D, G | NAG, CA | 10 (best 0.68) |
| 9FMU | Cryo-EM structure of human CD163 SRCR1-9 in complex with haptoglobin-hemoglobin | electron microscopy | D, E | CA, NAG | 16 (best 0.78) |
| Q86VB7 | AlphaFold monomer V2.0 prediction for scavenger receptor cysteine- rich type 1 protein M130 (Q86VB7) | predicted | A | — | — |
Ligands
Experiment against prediction
- 8XMK chain F against the predicted model Q86VB7: TM-score 0.97, RMSD 1.55 Å
- 8XMK chain D against the predicted model Q86VB7: TM-score 0.94, RMSD 2.05 Å
- 8XMK chain E against the predicted model Q86VB7: TM-score 0.91, RMSD 2.94 Å
- 9FMU chain E against the predicted model Q86VB7: TM-score 0.90, RMSD 3.04 Å
- 8XMP chain E against the predicted model Q86VB7: TM-score 0.90, RMSD 3.26 Å
- 8XMP chain F against the predicted model Q86VB7: TM-score 0.89, RMSD 3.73 Å
- 8XMP chain D against the predicted model Q86VB7: TM-score 0.89, RMSD 3.76 Å
- 9FMU chain D against the predicted model Q86VB7: TM-score 0.87, RMSD 3.73 Å
- 8XMW chain D against the predicted model Q86VB7: TM-score 0.84, RMSD 3.08 Å
- 8XMW chain G against the predicted model Q86VB7: TM-score 0.82, RMSD 3.52 Å
Elsewhere
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