UniProt Q86U70
LIM domain-binding protein 1 (Q86U70)
LIM domain-binding protein 1 (UniProt Q86U70): 15 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 12 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q86U70
- Protein
- LIM domain-binding protein 1
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 12 · 4 records with a druggable one
Structures
16 records of Q86U70 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2XJY | Crystal structure of the LMO2:LDB1-LID complex, P21 crystal form | x-ray diffraction | B | — | — |
| 2XJY | Crystal structure of the LMO2:LDB1-lid complex, P21 crystal form | x-ray diffraction | B | — | — |
| 2XJZ | Crystal structure of the LMO2:LDB1-LID complex, C2 crystal form | x-ray diffraction | I, J, K, L, M | — | — |
| 2XJZ | Crystal structure of the LMO2:LDB1-lid complex, C2 crystal form | x-ray diffraction | I, J, K, L, M | — | — |
| 2YPA | Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA | x-ray diffraction | D | — | — |
| 2YPA | Structure of the SCL:E47:LMO2:LDB1 complex bound to DNA | x-ray diffraction | D | — | — |
| 6TYD | Structure of human LDB1 in complex with SSBP2 | x-ray diffraction | V | — | 2 (best 0.60) |
| 6TYD | Structure of human LDB1 in complex with SSBP2 | x-ray diffraction | V | — | — |
| 7OB5 | Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide | x-ray diffraction | P | — | 1 (best 0.42) |
| 7OB5 | Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide | x-ray diffraction | P | — | — |
| 7OB8 | Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide and stabilizer Fusicoccin-A | x-ray diffraction | B | FSC | 1 (best 0.58) |
| 7OB8 | Crystal structure of 14-3-3 sigma in complex with LDB1 phosphopeptide and stabilizer fusicoccin-a | x-ray diffraction | B | FSC | — |
| 8HIB | The crystal structure of Pygo2-LDB1-SSBP2 triple complex | x-ray diffraction | V | — | 4 (best 0.64) |
| 8SSU | ZnFs 3-11 of CCCTC-binding factor (CTCF) Complexed with 19mer DNA | x-ray diffraction | A | ZN | 4 (best 0.55) |
| 9F5B | Identification of zinc ions in LMO4. | x-ray diffraction | A | ZN | — |
| Q86U70 | AlphaFold monomer V2.0 prediction for lim domain-binding protein 1 (Q86U70) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7OB8 chain B against the predicted model Q86U70: TM-score 1.00, RMSD 0.02 Å
- 7OB8 chain B against the predicted model Q86U70: TM-score 1.00, RMSD 0.02 Å
- 8HIB chain V against the predicted model Q86U70: TM-score 0.97, RMSD 0.95 Å
- 6TYD chain V against the predicted model Q86U70: TM-score 0.97, RMSD 1.06 Å
- 6TYD chain V against the predicted model Q86U70: TM-score 0.97, RMSD 1.06 Å
- 9F5B chain A against the predicted model P61968: TM-score 0.79, RMSD 1.55 Å
- 8SSU chain A against the predicted model P49711: TM-score 0.60, RMSD 3.66 Å
- 7OB5 chain P against the predicted model Q86U70: TM-score 0.44, RMSD 1.18 Å
- 7OB5 chain P against the predicted model Q86U70: TM-score 0.44, RMSD 1.18 Å
- 2XJZ chain I against the predicted model Q86U70: TM-score 0.33, RMSD 2.62 Å
Elsewhere
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