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UniProt Q82GL5

Cytochrome P450 hydroxylase (Q82GL5)

Cytochrome P450 hydroxylase (UniProt Q82GL5): 6 experimental structures on GenesisL1, 4 ligands bound, 8 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q82GL5
Protein
Cytochrome P450 hydroxylase
Experimental structures
6
Predicted models
0
Ligands
4
Pockets
8 · 2 records with a druggable one

Structures

6 records of Q82GL5 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6L69Crystal structure of CYP154C2 from streptomyces avermitilisx-ray diffractionA, BHEM—
7CL7Substrate-free structure of CYP154C2 from streptomyces avermitilis in an open conformationx-ray diffractionAHEM, CA—
7CL8Testosterone-bound structure of CYP154C2 from Streptomyces avermitilis in an closed conformationx-ray diffractionAHEM, TES5 (best 0.85)
7CL8Testosterone-bound structure of CYP154C2 from streptomyces avermitilis in an closed conformationx-ray diffractionAHEM, TES—
7CL9Androstenedione-bound structure of CYP154C2 from Streptomyces avermitilis in an open conformationx-ray diffractionAHEM, ASD3 (best 0.82)
7CL9Androstenedione-bound structure of CYP154C2 from streptomyces avermitilis in an open conformationx-ray diffractionAHEM, ASD, CA—

Ligands

  • HEM · Protoporphyrin IX containing Fe · in 6 records
  • ASD · 4-androstene-3-17-dione · in 2 records
  • CA · Calcium ion · in 2 records
  • TES · Testosterone · in 2 records

Elsewhere

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