UniProt Q80XZ4
Interleukin-22 receptor subunit alpha-1 (Q80XZ4)
Interleukin-22 receptor subunit alpha-1 (UniProt Q80XZ4): 2 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 18 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q80XZ4
- Protein
- Interleukin-22 receptor subunit alpha-1
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 18 · 1 record with a druggable one
Structures
3 records of Q80XZ4 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WEO | IL-22 Signaling Complex with IL-22R1 and IL-10Rbeta | x-ray diffraction | 1, 4, 7, A, B, F, I, M, P, S, V, Y | NAG, FUC | 18 (best 0.79) |
| 6WEO | Il-22 signaling complex with il-22R1 and il-10RBETA | x-ray diffraction | 1, 4, 7, A, B, F, I, M, P, S, V, Y | NAG, FUC | — |
| Q80XZ4 | AlphaFold monomer V2.0 prediction for interleukin-22 receptor subunit alpha-1 (Q80XZ4) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6WEO chain 7 against the predicted model Q80XZ4: TM-score 0.97, RMSD 0.99 Å
- 6WEO chain Y against the predicted model Q80XZ4: TM-score 0.97, RMSD 1.00 Å
- 6WEO chain M against the predicted model Q80XZ4: TM-score 0.97, RMSD 1.08 Å
- 6WEO chain 1 against the predicted model Q80XZ4: TM-score 0.97, RMSD 1.03 Å
- 6WEO chain 1 against the predicted model Q80XZ4: TM-score 0.97, RMSD 1.03 Å
- 6WEO chain I against the predicted model Q80XZ4: TM-score 0.96, RMSD 1.08 Å
- 6WEO chain S against the predicted model Q80XZ4: TM-score 0.96, RMSD 1.07 Å
- 6WEO chain 4 against the predicted model Q80XZ4: TM-score 0.96, RMSD 1.11 Å
- 6WEO chain P against the predicted model Q80XZ4: TM-score 0.96, RMSD 1.12 Å
- 6WEO chain A against the predicted model Q80XZ4: TM-score 0.95, RMSD 1.21 Å
Elsewhere
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