UniProt Q7ZUW7
Protein Mdm4 (Q7ZUW7)
Protein Mdm4 (UniProt Q7ZUW7): 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7ZUW7
- Protein
- Protein Mdm4
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 8 · 1 record with a druggable one
Structures
14 records of Q7ZUW7 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3DAC | Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain | x-ray diffraction | M, A | — | — |
| 3DAC | Structure of the human mdmx protein bound to the P53 tumor suppressor transactivation domain | x-ray diffraction | M, A | — | — |
| 4N5T | The 1.7A Crystal Structure of MDMX with a Stapled Peptide, ATSP-7041 | x-ray diffraction | A | — | — |
| 4N5T | The 1.7A crystal structure of mdmx with a stapled peptide, atsp-7041 | x-ray diffraction | A | — | — |
| 6V4E | Crystal Structure Analysis of Zebra Fish MDM | x-ray diffraction | A, B | — | 3 (best 0.37) |
| 6V4E | Crystal structure analysis of zebra fish mdm | x-ray diffraction | A, B | 0EH | — |
| 6V4F | Crystal Structure Analysis of Zebra Fish MDMX | x-ray diffraction | A | SO4 | — |
| 6V4F | Crystal structure analysis of zebra fish mdmx | x-ray diffraction | A | 0EH, SO4 | — |
| 6V4G | Crystal Structure Analysis of Zebra fish MDMX | x-ray diffraction | A | SO4 | — |
| 6V4G | Crystal structure analysis of zebra fish mdmx | x-ray diffraction | A | 0EH, SO4 | — |
| 6V4H | Crystal Structure Analysis of Zebra Fish MDMX | x-ray diffraction | A, C | — | 2 (best 0.42) |
| 6V4H | Crystal structure analysis of zebra fish mdmx | x-ray diffraction | A, C | 0EH | — |
| 8GJS | Stapled Peptide ALRN-6924 Bound to MDMX | x-ray diffraction | A | — | — |
| Q7ZUW7 | AlphaFold monomer V2.0 prediction for protein MDM4 (Q7ZUW7) | predicted | A | — | 3 (best 0.62) |
Ligands
Experiment against prediction
- 3DAC chain M against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.27 Å
- 3DAC chain M against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.27 Å
- 6V4H chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.31 Å
- 6V4H chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.31 Å
- 4N5T chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.31 Å
- 4N5T chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.31 Å
- 6V4G chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.32 Å
- 6V4G chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.32 Å
- 8GJS chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.32 Å
- 6V4F chain A against the predicted model Q7ZUW7: TM-score 0.99, RMSD 0.34 Å
Elsewhere
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