UniProt Q7Z6M4
Transcription termination factor 4, mitochondrial (Q7Z6M4)
Transcription termination factor 4, mitochondrial (UniProt Q7Z6M4): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 4 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- Q7Z6M4
- Protein
- Transcription termination factor 4, mitochondrial
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 4 · 2 records with a druggable one
Structures
19 records of Q7Z6M4 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4FP9 | Human MTERF4-NSUN4 protein complex | x-ray diffraction | B, E, G, H | — | — |
| 4FP9 | Human MTERF4-NSUN4 protein complex | x-ray diffraction | B, E, G, H | — | — |
| 4FZV | Crystal structure of the human MTERF4:NSUN4:SAM ternary complex | x-ray diffraction | B | — | — |
| 4FZV | Crystal structure of the human MTERF4:NSUN4:SAM ternary complex | x-ray diffraction | B | — | — |
| 7O9K | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1, the… | electron microscopy | A2 | — | — |
| 7O9M | Human mitochondrial ribosome large subunit assembly intermediate with MTERF4-NSUN4, MRM2, MTG1 and… | electron microscopy | A2 | — | 1 (best 0.82) |
| 7ODR | State A of the human mitoribosomal large subunit assembly intermediate | electron microscopy | y | — | — |
| 7ODS | State B of the human mitoribosomal large subunit assembly intermediate | electron microscopy | y | — | — |
| 7ODT | State C of the human mitoribosomal large subunit assembly intermediate | electron microscopy | y | — | — |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | G | — | — |
| 7OF0 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | G | — | — |
| 7OF3 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | G | — | — |
| 7OF5 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | G | — | — |
| 7OF7 | Structure of a human mitochondrial ribosome large subunit assembly intermediate in complex with… | electron microscopy | G | — | — |
| 7OIC | Cryo-EM structure of late human 39S mitoribosome assembly intermediates, state 4 | electron microscopy | y | — | — |
| 7PD3 | Structure of the human mitoribosomal large subunit in complex with NSUN4.MTERF4.GTPBP7 and… | electron microscopy | y | A, G | — |
| 8PK0 | human mitoribosomal large subunit assembly intermediate 1 with GTPBP10-GTPBP7 | electron microscopy | y | — | — |
| 8QSJ | Human mitoribosomal large subunit assembly intermediate 2 with GTPBP7 | electron microscopy | y | — | — |
| Q7Z6M4 | AlphaFold monomer V2.0 prediction for transcription termination factor 4, mitochondrial (Q7Z6M4) | predicted | A | — | 3 (best 0.57) |
Ligands
Experiment against prediction
- 4FP9 chain B against the predicted model Q7Z6M4: TM-score 0.99, RMSD 0.49 Å
- 4FP9 chain B against the predicted model Q7Z6M4: TM-score 0.99, RMSD 0.49 Å
- 4FZV chain B against the predicted model Q7Z6M4: TM-score 0.97, RMSD 1.11 Å
- 4FZV chain B against the predicted model Q7Z6M4: TM-score 0.97, RMSD 1.11 Å
- 7PD3 chain y against the predicted model Q7Z6M4: TM-score 0.92, RMSD 1.82 Å
- 7OF3 chain G against the predicted model Q7Z6M4: TM-score 0.91, RMSD 1.86 Å
- 7OIC chain y against the predicted model Q7Z6M4: TM-score 0.91, RMSD 1.81 Å
- 7OF5 chain G against the predicted model Q7Z6M4: TM-score 0.91, RMSD 1.90 Å
- 7ODS chain y against the predicted model Q7Z6M4: TM-score 0.90, RMSD 1.98 Å
- 7O9M chain A2 against the predicted model Q7Z6M4: TM-score 0.90, RMSD 1.98 Å
Elsewhere
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