UniProt Q7Z6A9
B- and T-lymphocyte attenuator (Q7Z6A9)
B- and T-lymphocyte attenuator (UniProt Q7Z6A9): 7 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 20 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7Z6A9
- Protein
- B- and T-lymphocyte attenuator
- Experimental structures
- 7
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 20 · 4 records with a druggable one
Structures
8 records of Q7Z6A9 in the MolNFT archive: 7 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2AW2 | Crystal structure of the human BTLA-HVEM complex | x-ray diffraction | A, X | NI | 8 (best 0.73) |
| 2AW2 | Crystal structure of the human btla-hvem complex | x-ray diffraction | A, X | — | — |
| 6NYP | Crystal structure of UL144/BTLA complex | x-ray diffraction | A, B, C, D | SO4, NA | 6 (best 0.81) |
| 6NYP | Crystal structure of UL144/BTLA complex | x-ray diffraction | A, B, C, D | SO4, NA | — |
| 8F60 | anti-BTLA monoclonal antibody r23C8 in complex with BTLA | x-ray diffraction | C | NAG | 1 (best 0.54) |
| 8F6L | anti-BTLA monoclonal antibody h25F7 in complex with BTLA | x-ray diffraction | C | — | 4 (best 0.59) |
| 8F6O | anti-BTLA monoclonal antibody h22B3 in complex with BTLA | x-ray diffraction | C | — | 1 (best 0.34) |
| Q7Z6A9 | AlphaFold monomer V2.0 prediction for B- and T-lymphocyte attenuator (Q7Z6A9) | predicted | A | — | — |
Ligands
Experiment against prediction
- 6NYP chain A against the predicted model Q7Z6A9: TM-score 0.98, RMSD 0.60 Å
- 6NYP chain A against the predicted model Q7Z6A9: TM-score 0.98, RMSD 0.60 Å
- 6NYP chain B against the predicted model Q7Z6A9: TM-score 0.97, RMSD 0.62 Å
- 6NYP chain B against the predicted model Q7Z6A9: TM-score 0.97, RMSD 0.62 Å
- 6NYP chain C against the predicted model Q7Z6A9: TM-score 0.97, RMSD 0.90 Å
- 6NYP chain C against the predicted model Q7Z6A9: TM-score 0.97, RMSD 0.90 Å
- 6NYP chain D against the predicted model Q7Z6A9: TM-score 0.96, RMSD 1.02 Å
- 6NYP chain D against the predicted model Q7Z6A9: TM-score 0.96, RMSD 1.02 Å
- 2AW2 chain A against the predicted model Q7Z6A9: TM-score 0.95, RMSD 1.42 Å
- 2AW2 chain A against the predicted model Q7Z6A9: TM-score 0.95, RMSD 1.42 Å
Elsewhere
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