UniProt Q7Z3C6
Autophagy-related protein 9A (Q7Z3C6)
Autophagy-related protein 9A (UniProt Q7Z3C6): 13 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 142 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7Z3C6
- Protein
- Autophagy-related protein 9A
- Experimental structures
- 13
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 142 · 8 records with a druggable one
Structures
14 records of Q7Z3C6 in the MolNFT archive: 13 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WQZ | Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery | electron microscopy | C, F, B, A, E, D | LMN | 20 (best 0.76) |
| 6WQZ | Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery | electron microscopy | C, F, B, A, E, D | LMN | — |
| 6WR4 | Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery | electron microscopy | A, B, C | LMN | 20 (best 0.74) |
| 6WR4 | Structure of human ATG9A, the only transmembrane protein of the core autophagy machinery | electron microscopy | A, B, C | LMN | — |
| 7JLO | Cryo-EM structure of human ATG9A in amphipols | electron microscopy | A, B, C | — | 20 (best 0.75) |
| 7JLO | Cryo-EM structure of human ATG9A in amphipols | electron microscopy | A, B, C | — | — |
| 7JLP | cryo-EM structure of human ATG9A in nanodiscs | electron microscopy | A, B, C | POV | 20 (best 0.76) |
| 7JLP | Cryo-EM structure of human ATG9A in nanodiscs | electron microscopy | A, B, C | POV | — |
| 7JLQ | cryo-EM structure of human ATG9A in LMNG micelles | electron microscopy | A, B, C | — | 20 (best 0.76) |
| 7JLQ | Cryo-EM structure of human ATG9A in lmng micelles | electron microscopy | A, B, C | — | — |
| 8KBZ | Cryo-EM structure of human ATG9A in LMNG micelles | electron microscopy | A, B, C | — | 20 (best 0.76) |
| 8KC3 | Cryo-EM structure of human C-terminally bound ATG9A-ATG2A-WIPI4 complex | electron microscopy | A, B, C | — | 11 (best 0.77) |
| 8Y1L | Cryo-EM structure of human N-terminally bound ATG9A-ATG2A-WIPI4 complex | electron microscopy | C, D, E | — | 11 (best 0.76) |
| Q7Z3C6 | AlphaFold monomer V2.0 prediction for autophagy-related protein 9A (Q7Z3C6) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7JLP chain B against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.76 Å
- 7JLP chain C against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.76 Å
- 7JLP chain B against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.76 Å
- 7JLP chain C against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.76 Å
- 7JLP chain A against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.76 Å
- 7JLP chain A against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.76 Å
- 7JLO chain C against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.86 Å
- 7JLO chain C against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.86 Å
- 7JLO chain B against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.86 Å
- 7JLO chain B against the predicted model Q7Z3C6: TM-score 0.99, RMSD 0.86 Å
Elsewhere
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