UniProt Q7WYA8
Beta-lactamase (Q7WYA8)
Beta-lactamase (UniProt Q7WYA8), EC 3.5.2.6: 8 experimental structures on GenesisL1, 8 ligands bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7WYA8
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 8
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 14 · 3 records with a druggable one
Structures
8 records of Q7WYA8 in the MolNFT archive: 8 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6R73 | Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed meropenem | x-ray diffraction | A, B | LMP, ZN | 3 (best 0.71) |
| 6R73 | Structure of imp-13 metallo-beta-lactamase complexed with hydrolysed meropenem | x-ray diffraction | A, B | LMP, ZN | — |
| 6R79 | Structure of IMP-13 metallo-beta-lactamase in apo form (loop open) | x-ray diffraction | A, B, C, D | GLY, ZN, NA, PO4 | 7 (best 0.81) |
| 6R79 | Structure of imp-13 metallo-beta-lactamase in apo form (loop open) | x-ray diffraction | A, B, C, D | ZN, PO4 | — |
| 6RZR | Structure of imp-13 metallo-beta-lactamase complexed with hydrolysed imipenem | x-ray diffraction | A, B | ZN, 8YF | — |
| 6RZS | Structure of imp-13 metallo-beta-lactamase complexed with hydrolysed ertapenem | x-ray diffraction | A, B | LHT, ZN | — |
| 6S0H | Structure of IMP-13 metallo-beta-lactamase complexed with hydrolysed doripenem | x-ray diffraction | A, B | ZN, KQ8 | 4 (best 0.71) |
| 6S0H | Structure of imp-13 metallo-beta-lactamase complexed with hydrolysed doripenem | x-ray diffraction | A, B | ZN, KQ8 | — |
Ligands
- ZN · Zinc ion · in 8 records
- KQ8 · (2~{R},3~{R})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-3-methyl-4-[(3~{S},5~{S})-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]sulfanyl-2,3-dihydro-1~{H}-pyrrole-5-carboxylic acid · in 2 records
- LMP · (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid · in 2 records
- PO4 · Phosphate ion · in 2 records
- 8YF · (2R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-(2-methanimidamidoethylsulfanyl)-2,3-dihydro-1H-pyrrole-5-carboxylic acid · in 1 record
- GLY · Glycine · in 1 record
- LHT · Hydrolysed ertapenem · in 1 record
- NA · Sodium ion · in 1 record
Elsewhere
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