UniProt Q7SSI0
Protease (Q7SSI0)
Protease (UniProt Q7SSI0): 25 experimental structures on GenesisL1, 5 ligands bound, 4 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7SSI0
- Protein
- Protease
- Experimental structures
- 25
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 4 · 4 records with a druggable one
Structures
25 records of Q7SSI0 in the MolNFT archive: 25 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3NDU | HIV-1 Protease Saquinavir:Ritonavir 1:5 complex structure | x-ray diffraction | A, B, C, D | — | — |
| 3NDU | HIV-1 protease SAQUINAVIR:RITONAVIR 1:5 complex structure | x-ray diffraction | A, B, C, D | — | — |
| 3NDW | HIV-1 Protease Saquinavir:Ritonavir 1:15 complex structure | x-ray diffraction | A, B | — | — |
| 3NDW | HIV-1 protease SAQUINAVIR:RITONAVIR 1:15 complex structure | x-ray diffraction | A, B | — | — |
| 3NDX | HIV-1 Protease Saquinavir:Ritonavir 1:50 complex structure | x-ray diffraction | A, B | — | — |
| 3NDX | HIV-1 protease SAQUINAVIR:RITONAVIR 1:50 complex structure | x-ray diffraction | A, B | — | — |
| 3OXC | Wild Type HIV-1 Protease with Antiviral Drug Saquinavir | x-ray diffraction | A, B | — | — |
| 3OXC | Wild type HIV-1 protease with antiviral drug saquinavir | x-ray diffraction | A, B | — | — |
| 3S53 | HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P212121 | x-ray diffraction | A, B | — | — |
| 3S53 | HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P212121 | x-ray diffraction | A, B | — | — |
| 3S54 | HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212 | x-ray diffraction | A, B | — | — |
| 3S54 | HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug darunavir in space group P21212 | x-ray diffraction | A, B | — | — |
| 3S56 | HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug saquinavir | x-ray diffraction | A, B | — | — |
| 3S56 | HIV-1 protease triple mutants V32I, I47V, V82I with antiviral drug saquinavir | x-ray diffraction | A, B | — | — |
| 4KB9 | Crystal structure of wild-type HIV-1 protease with novel tricyclic P2-ligands GRL-0739A | x-ray diffraction | A, B | — | — |
| 4KB9 | Crystal structure of wild-type HIV-1 protease with novel tricyclic P2- ligands grl-0739A | x-ray diffraction | A, B | — | — |
| 5E5J | Joint X-ray/neutron structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with darunavir at pH… | x-ray diffraction, neutron diffraction | A, B | 017 | 1 (best 0.71) |
| 5E5J | Joint X-RAY/NEUTRON structure of HIV-1 protease triple mutant (V32I, I47V,V82I) with darunavir at… | x-ray diffraction; neutron diffraction | A, B | — | — |
| 5T8H | Joint X-ray/neutron structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with amprenavir at… | neutron diffraction, x-ray diffraction | A, B | 478 | 1 (best 0.71) |
| 5T8H | Joint X-RAY/NEUTRON structure of HIV-1 protease triple mutant (V32I, I47V,V82I) with amprenavir at… | neutron diffraction; x-ray diffraction | A, B | 478 | — |
| 6OTG | HIV-1 protease triple mutants V32I, I47V, V82I with GRL-011-11A (a methylamine bis-Tetrahydrofuran… | x-ray diffraction | A, B | 4UY | 1 (best 0.70) |
| 6OTG | HIV-1 protease triple mutants V32I, I47V, V82I with grl-011-11A (a methylamine bis-tetrahydrofuran… | x-ray diffraction | A, B | 4UY | — |
| 6PTP | Joint X-RAY/NEUTRON structure of HIV-1 protease triple mutant (V32I, I47V,V82I) with tetrahedral… | x-ray diffraction; neutron diffraction | A, B | KVS | — |
| 6PU8 | Room temperature X-ray structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with tetrahedral… | x-ray diffraction | A, B | P3V | 1 (best 0.71) |
| 6PU8 | Room temperature X-ray structure of HIV-1 protease triple mutant (V32I,I47V,V82I) with tetrahedral… | x-ray diffraction | A, B | P3V | — |
Ligands
- 478 · {3-[(4-amino-benzenesulfonyl)-isobutyl-amino]-1-benzyl-2-hydroxy-propyl}-carbamic acid tetrahydro-furan-3-yl ester · in 2 records
- 4UY · (3r,3as,4r,6ar)-4-(methylamino)hexahydrofuro[2,3-b]furan-3-yl [(2S,3R)-3-hydroxy-4-{[(4-methoxyphenyl) sulfonyl](2-methylpropyl)amino}-1-phenylbutan-2-yl]carbamate · in 2 records
- P3V · (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S)-4-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-3,3-dihydroxy-1-phenylbutan-2-yl]carbamate · in 2 records
- 017 · (3r,3as,6ar)-hexahydrofuro[2,3-b]furan-3-yl(1s,2r)-3-[[(4-aminophenyl)sulfonyl](isobutyl)amino]-1-benzyl-2-hydroxypropylcarbamate · in 1 record
- KVS · N~2~-[(2R,5S)-5-({(2S,3S)-2-[(N-acetyl-L-threonyl) amino]-3-methylpent-4-enoyl}amino)-2-butyl-4,4-dihydroxynonanoyl]-L-glutaminyl-L-argininamide · in 1 record
Elsewhere
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