UniProt Q7LHG5
Transposon Ty3-I Gag-Pol polyprotein (Q7LHG5)
Transposon Ty3-I Gag-Pol polyprotein (UniProt Q7LHG5), EC 2.7.7.49, 2.7.7.7: 6 experimental structures and 1 predicted model on GenesisL1, 23 pockets. Binding sites, druggability and experiment against prediction (TM-score) in…
- UniProt
- Q7LHG5
- Protein
- Transposon Ty3-I Gag-Pol polyprotein
- EC
- 2.7.7.49, 2.7.7.7, 3.1.26.4, 3.4.23.-
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 23 · 3 records with a druggable one
Structures
7 records of Q7LHG5 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6R22 | The structure of a Ty3 retrotransposon capsid N-terminal domain dimer | electron microscopy | A, B | — | 3 (best 0.67) |
| 6R22 | The structure of a TY3 retrotransposon capsid N-terminal domain dimer | electron microscopy | A, B | — | — |
| 6R23 | The structure of a Ty3 retrotransposon capsid C-terminal domain dimer | electron microscopy | A, B | — | 3 (best 0.65) |
| 6R23 | The structure of a TY3 retrotransposon capsid C-terminal domain dimer | electron microscopy | A, B | — | — |
| 6R24 | The structure of a Ty3 retrotransposon icosahedral capsid | electron microscopy | A, B, C, D, E, F, G, H, I | — | 2 (best 0.32) |
| 6R24 | The structure of a TY3 retrotransposon icosahedral capsid | electron microscopy | A, B, C, D, E, F, G, H, I | — | — |
| Q7LHG5 | AlphaFold monomer V2.0 prediction for transposon TY3-I gag-pol polyprotein (Q7LHG5) | predicted | A | — | 15 (best 0.73) |
Experiment against prediction
- 6R23 chain A against the predicted model Q7LHG5: TM-score 0.75, RMSD 2.13 Å
- 6R23 chain A against the predicted model Q7LHG5: TM-score 0.75, RMSD 2.13 Å
- 6R23 chain B against the predicted model Q7LHG5: TM-score 0.75, RMSD 2.13 Å
- 6R22 chain B against the predicted model Q7LHG5: TM-score 0.64, RMSD 2.37 Å
- 6R22 chain A against the predicted model Q7LHG5: TM-score 0.64, RMSD 2.37 Å
- 6R22 chain A against the predicted model Q7LHG5: TM-score 0.64, RMSD 2.37 Å
- 6R24 chain H against the predicted model Q7LHG5: TM-score 0.47, RMSD 2.47 Å
- 6R24 chain B against the predicted model Q7LHG5: TM-score 0.47, RMSD 2.54 Å
- 6R24 chain B against the predicted model Q7LHG5: TM-score 0.47, RMSD 2.54 Å
- 6R24 chain I against the predicted model Q7LHG5: TM-score 0.47, RMSD 2.50 Å
Elsewhere
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