UniProt Q7L0Y3
tRNA methyltransferase 10 homolog C (Q7L0Y3)
tRNA methyltransferase 10 homolog C (UniProt Q7L0Y3), EC 2.1.1.-, 2.1.1.218: 12 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 83 pockets. Binding sites, druggability and experiment against…
- UniProt
- Q7L0Y3
- Protein
- tRNA methyltransferase 10 homolog C
- EC
- 2.1.1.-, 2.1.1.218, 2.1.1.221
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 83 · 9 records with a druggable one
Structures
13 records of Q7L0Y3 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NFJ | Crystal structure of the methyltransferase subunit of human mitochondrial Ribonuclease P (MRPP1)… | x-ray diffraction | A, B, C | — | — |
| 5NFJ | Crystal structure of the methyltransferase subunit of human mitochondrial ribonuclease P (MRPP1)… | x-ray diffraction | A, B, C | — | — |
| 7ONU | Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-Tyr | electron microscopy | F | — | 12 (best 0.81) |
| 7ONU | Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-tyr | electron microscopy | F | — | — |
| 8CBK | Structure of human mitochondrial RNase P in complex with mitochondrial pre-tRNA-His(5,Ser) | electron microscopy | F | SAH | 11 (best 0.80) |
| 8CBL | Structure of human mitochondrial RNase Z in complex with mitochondrial pre-tRNA-His(0,Ser) | electron microscopy | F | NAD, SAH | 9 (best 0.81) |
| 8CBM | Structure of human mitochondrial CCA-adding enzyme in complex with mitochondrial pre-tRNA-Ile | electron microscopy | F | NAD, SAH | 11 (best 0.83) |
| 8CBO | Structure of human mitochondrial MRPP1-MRPP2 in complex with mitochondrial pre-tRNA-Ile | electron microscopy | E | — | — |
| 9EY0 | Human mitochondrial RNase Z with tRNA-His | electron microscopy | F | SAM | 10 (best 0.81) |
| 9EY1 | Human mitochondrial RNase Z with tRNA-His precursor | electron microscopy | F | SAH | 10 (best 0.86) |
| 9EY2 | Human mitochondrial RNase Z with tRNA-His-CCA | electron microscopy | F | SAM | 9 (best 0.85) |
| 9GCH | Human mitochondrial RNase Z with tRNA-His-CCA, SDR5C1/TRMT10C focus | electron microscopy | F | SAM, MG | 8 (best 0.84) |
| Q7L0Y3 | AlphaFold monomer V2.0 prediction for tRNA methyltransferase 10 homolog C (Q7L0Y3) | predicted | A | — | 3 (best 0.72) |
Ligands
Experiment against prediction
- 5NFJ chain B against the predicted model Q7L0Y3: TM-score 0.97, RMSD 1.00 Å
- 5NFJ chain B against the predicted model Q7L0Y3: TM-score 0.97, RMSD 1.00 Å
- 8CBO chain E against the predicted model Q7L0Y3: TM-score 0.97, RMSD 1.17 Å
- 5NFJ chain A against the predicted model Q7L0Y3: TM-score 0.95, RMSD 1.27 Å
- 5NFJ chain A against the predicted model Q7L0Y3: TM-score 0.95, RMSD 1.27 Å
- 9EY0 chain F against the predicted model Q7L0Y3: TM-score 0.94, RMSD 1.74 Å
- 9EY2 chain F against the predicted model Q7L0Y3: TM-score 0.93, RMSD 1.87 Å
- 9GCH chain F against the predicted model Q7L0Y3: TM-score 0.93, RMSD 1.89 Å
- 9EY1 chain F against the predicted model Q7L0Y3: TM-score 0.93, RMSD 1.89 Å
- 8CBL chain F against the predicted model Q7L0Y3: TM-score 0.93, RMSD 1.82 Å
Elsewhere
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