UniProt Q7L0J3
Synaptic vesicle glycoprotein 2A (Q7L0J3)
Synaptic vesicle glycoprotein 2A (UniProt Q7L0J3): 13 experimental structures on GenesisL1, 7 ligands bound, 75 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7L0J3
- Protein
- Synaptic vesicle glycoprotein 2A
- Experimental structures
- 13
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 75 · 8 records with a druggable one
Structures
13 records of Q7L0J3 in the MolNFT archive: 13 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V11 | Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 | x-ray diffraction | B | — | — |
| 4V11 | Structure of synaptotagmin-1 with SV2A peptide phosphorylated at THR84 | x-ray diffraction | B | — | — |
| 8JLC | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam | electron microscopy | A | NAG, FUC, UKX | 8 (best 0.83) |
| 8JLE | Cryo-EM structure of SV2A LD4 in complex with BoNT/A2 Hc in the SV2A-levetiracetam-BoNT/A2 Hc… | electron microscopy | A | NAG, FUC | 2 (best 0.46) |
| 8JLF | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | electron microscopy | A | NAG, FUC | 7 (best 0.83) |
| 8JLG | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | electron microscopy | A | NAG, FUC | 2 (best 0.48) |
| 8JLH | Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam | electron microscopy | A, C | NAG, FUC, UKX | 9 (best 0.82) |
| 8JLI | Cryo-EM structure of SV2A dimer in complex levetiracetam | electron microscopy | A, B | UKX | 8 (best 0.83) |
| 8JS9 | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc | electron microscopy | A | NAG, FUC | 6 (best 0.82) |
| 8K77 | Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and brivaracetam | electron microscopy | A | NAG, FUC, VLX | 7 (best 0.82) |
| 8UO9 | Structure of synaptic vesicle protein 2A in complex with a nanobody | electron microscopy | A | NAG, X49, Y01, PS1 | 6 (best 0.82) |
| 8YF0 | Cryo-EM structure of human SV2A | electron microscopy | B, C | — | 20 (best 0.81) |
| Q7L0J3 | AlphaFold monomer V2.0 prediction for synaptic vesicle glycoprotein 2A (Q7L0J3) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 8 records
- FUC · alpha-L-fucopyranose · in 7 records
- UKX · (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide · in 3 records
- PS1 · 1,2-didecanoyl-sn-glycero-3-[phospho-L-serine] · in 1 record
- VLX · (2S)-2-[(4R)-2-oxidanylidene-4-propyl-pyrrolidin-1-yl]butanamide · in 1 record
- X49 · (4S)-1-{[(4S)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}-4-(4,4,4-trifluorobutyl)pyrrolidin-2-one · in 1 record
- Y01 · Cholesterol hemisuccinate · in 1 record
Elsewhere
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