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Ligand · UKX

UKX · (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide

UKX, (2S)-2-(2-oxidanylidenepyrrolidin-1-yl)butanamide (C8 H14 N2 O2, 170.2 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most…

Component
UKX
Formula
C8 H14 N2 O2
Class
ligand
Structures
4
PDB entries
4

Binding sites

UKX in 4 structures; the first of them:

  • 8JLC · Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam · UKX A803 · binds LEU176, ILE273, PHE277, TRP300, TRP454, TYR461, TYR462, ILE663 and 3 more
  • 8JLH · Cryo-EM structure of SV2A dimer in complex with BoNT/A2 Hc and levetiracetam · UKX A801 · binds LEU176, ILE273, PHE277, TRP300, TRP454, TYR461, TYR462, ILE663 and 4 more
  • 8JLI · Cryo-EM structure of SV2A dimer in complex levetiracetam · UKX A801 · binds ILE273, PHE277, CYS297, TRP300, TYR461, TYR462, ILE663, TRP666 and 2 more
  • 8JS8 · Cryo-EM structure of SV2A in complex with BoNT/A2 Hc and levetiracetam · UKX A803 · binds LEU176, ILE273, PHE277, TRP300, TRP454, TYR461, TYR462, ILE663 and 4 more

Residues it binds most

TRP 5, ILE 5, TYR 5, ASN 5, ASP 5, PHE 5, LEU 3, CYS 2, LYS 2 (residue and the binding sites it lines).

Found with

  • FUC · alpha-L-fucopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose

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