UniProt Q7IIB7
NADH-ubiquinone oxidoreductase chain 4 (Q7IIB7)
NADH-ubiquinone oxidoreductase chain 4 (UniProt Q7IIB7), EC 7.1.1.2: 44 experimental structures on GenesisL1, 4 ligands bound, 182 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7IIB7
- Protein
- NADH-ubiquinone oxidoreductase chain 4
- EC
- 7.1.1.2
- Experimental structures
- 44
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 182 · 25 records with a druggable one
Structures
44 records of Q7IIB7 in the MolNFT archive: 44 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7V2C | Active state complex I from Q10 dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | r | CDL, PEE, PLX | 5 (best 0.87) |
| 7V2D | Deactive state complex I from Q10 dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | r | PEE, CDL, PLX | 7 (best 0.88) |
| 7V2E | Active state complex I from Q10-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | r | PEE, CDL, PLX | 7 (best 0.90) |
| 7V2F | Deactive state complex I from Q10-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V2H | Active state complex I from dq-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V2K | Deactive state complex I from DQ-NADH dataset | electron microscopy | r | PEE, PLX, CDL | 7 (best 0.87) |
| 7V2K | Deactive state complex I from dq-NADH dataset | electron microscopy | r | PEE, PLX, CDL | — |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | r | PEE, CDL, PLX | 7 (best 0.89) |
| 7V2R | Active state complex I from Q1-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | r | PEE, CDL, PLX | 7 (best 0.87) |
| 7V30 | Deactive state complex I from Q1-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V31 | Active state complex I from rotenone dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V32 | Deactive state complex I from rotenone dataset | electron microscopy | r | CDL, PLX, PEE | — |
| 7V33 | Active state complex I from rote -NADH dataset | electron microscopy | r | CDL, PLX, PEE | 6 (best 0.87) |
| 7V33 | Active state complex I from rotenone-NADH dataset | electron microscopy | r | CDL, PLX, PEE | — |
| 7V3M | Deactive state complex I from rote -NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7V3M | Deactive state complex I from rotenone-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7VBL | Membrane arm of active state ci from dq-NADH dataset | electron microscopy | r | CDL, PLX, PEE | — |
| 7VBP | Membrane arm of deactive state CI from DQ-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7VBP | Membrane arm of deactive state ci from dq-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7VC0 | Membrane arm of active state ci from rotenone-NADH dataset | electron microscopy | r | PEE, CDL, PLX | — |
| 7VWL | Membrane arm of deactive state ci from rotenone-NADH dataset | electron microscopy | r | CDL, PLX, PEE | — |
| 7VXS | Membrane arm of active state CI from Q10 dataset | electron microscopy | r | CDL, PEE, PLX | 10 (best 0.90) |
| 7VY1 | Membrane arm of deactive state CI from Q10 dataset | electron microscopy | r | CDL, PLX, PEE | 12 (best 0.87) |
| 7VYE | Membrane arm of deactive state CI from Q10-NADH dataset | electron microscopy | r | CDL, PLX, PEE | 13 (best 0.89) |
| 7VYS | Membrane arm of active state CI from Q1-NADH dataset | electron microscopy | r | CDL, PLX, PEE, TYR | 12 (best 0.88) |
| 7VZW | Active state CI from Q10 dataset, Subclass 2 | electron microscopy | r | PEE, CDL, PLX | 6 (best 0.88) |
| 7W0H | Deactive state CI from Q10 dataset, Subclass 2 | electron microscopy | r | CDL, PLX, PEE | 6 (best 0.88) |
| 7W1O | Deactive state CI from Q10-NADH dataset, Subclass 1 | electron microscopy | r | CDL, PLX, PEE | 8 (best 0.89) |
| 7W1U | Active state CI from Rote dataset, Subclass 2 | electron microscopy | r | CDL, PLX, PEE | 5 (best 0.86) |
| 7W1V | Active state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | r | CDL, PLX, PEE | 7 (best 0.88) |
| 7W20 | Active state CI from Rote -NADH dataset, Subclass 3 | electron microscopy | r | CDL, PLX, PEE | 5 (best 0.88) |
| 7W2K | Deactive state CI from Rote -NADH dataset, Subclass 1 | electron microscopy | r | PEE, CDL, PLX | 8 (best 0.89) |
| 7W2L | Deactive state CI from Rote -NADH dataset, Subclass 2 | electron microscopy | r | PEE, CDL, PLX | 8 (best 0.89) |
| 7W2R | Active state CI from DQ-NADH dataset, Subclass 1 | electron microscopy | r | CDL, PLX, PEE | 7 (best 0.88) |
| 7W2U | Active state CI from DQ-NADH dataset, Subclass 2 | electron microscopy | r | CDL, PLX, PEE | 6 (best 0.87) |
| 7W35 | Deactive state CI from DQ-NADH dataset, Subclass 3 | electron microscopy | r | CDL, PEE, PLX | 7 (best 0.89) |
| 7W4G | Active state CI from Q1-NADH dataset, Subclass 5 | electron microscopy | r | PEE, CDL, PLX | 5 (best 0.88) |
| 7W4J | Deactive state CI from Q1-NADH dataset, Subclass 1 | electron microscopy | r | CDL, PLX, PEE | — |
| 7W4N | Deactive state CI from Q1-NADH dataset, Subclass 5 | electron microscopy | r | CDL, PEE, PLX | 6 (best 0.86) |
| 7W4Q | Deactive state CI from Q1-NADH dataset, Subclass 6 | electron microscopy | r | PEE, CDL, PLX | 5 (best 0.89) |
Ligands
Elsewhere
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