UniProt Q7BSW5
Serine protease EspP (Q7BSW5)
Serine protease EspP (UniProt Q7BSW5), EC 3.4.21.-, 5.2.1.8: 35 experimental structures and 1 predicted model on GenesisL1, 48 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q7BSW5
- Protein
- Serine protease EspP
- EC
- 3.4.21.-, 5.2.1.8
- Experimental structures
- 35
- Predicted models
- 1
- Pockets
- 48 · 12 records with a druggable one
Structures
36 records of Q7BSW5 in the MolNFT archive: 35 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2QOM | The crystal structure of the E.coli EspP autotransporter Beta-domain. | x-ray diffraction | A, B | — | — |
| 2QOM | The crystal structure of the E.COLI espp autotransporter beta-domain. | x-ray diffraction | A, B | — | — |
| 3SLJ | Pre-cleavage Structure of the Autotransporter EspP - N1023A mutant | x-ray diffraction | A | — | — |
| 3SLJ | Pre-cleavage structure of the autotransporter espp - N1023A mutant | x-ray diffraction | A | — | — |
| 3SLO | Pre-cleavage Structure of the Autotransporter EspP - N1023D mutant | x-ray diffraction | A | — | — |
| 3SLO | Pre-cleavage structure of the autotransporter espp - N1023D mutant | x-ray diffraction | A | — | — |
| 3SLT | Pre-cleavage Structure of the Autotransporter EspP - N1023S Mutant | x-ray diffraction | A | — | — |
| 3SLT | Pre-cleavage structure of the autotransporter espp - N1023S mutant | x-ray diffraction | A | — | — |
| 3SZE | Crystal structure of the passenger domain of the E. coli autotransporter EspP | x-ray diffraction | A | — | — |
| 3SZE | Crystal structure of the passenger domain of the E. COLI autotransporter espp | x-ray diffraction | A | — | — |
| 7TSZ | BamABCDE bound to substrate EspP class 1 | electron microscopy | P | — | 2 (best 0.80) |
| 7TSZ | Bamabcde bound to substrate espp class 1 | electron microscopy | P | — | — |
| 7TT0 | Bamabcde bound to substrate espp class 2 | electron microscopy | P | — | — |
| 7TT1 | BamABCDE bound to substrate EspP class 4 | electron microscopy | P | — | 3 (best 0.78) |
| 7TT1 | Bamabcde bound to substrate espp class 4 | electron microscopy | P | — | — |
| 7TT2 | BamABCDE bound to substrate EspP class 3 | electron microscopy | P | — | — |
| 7TT2 | Bamabcde bound to substrate espp class 3 | electron microscopy | P | — | — |
| 7TT3 | Bamabcde bound to substrate espp class 5 | electron microscopy | P | — | — |
| 7TT4 | Bamabcde bound to substrate espp class 6 | electron microscopy | P | — | — |
| 7TT5 | Bamabcde bound to substrate espp in the open-sheet espp state | electron microscopy | P | — | — |
| 7TT6 | BamABCDE bound to substrate EspP in the intermediate-open EspP state | electron microscopy | P | — | 4 (best 0.82) |
| 7TT6 | Bamabcde bound to substrate espp in the intermediate-open espp state | electron microscopy | P | — | — |
| 7TT7 | BamABCDE bound to substrate EspP in the barrelized EspP/continuous open BamA state | electron microscopy | P | — | — |
| 7TT7 | Bamabcde bound to substrate espp in the barrelized ESPP/CONTINUOUS open bama state | electron microscopy | P | — | — |
| 7TTC | BamABCDE bound to substrate EspP | electron microscopy | P | — | 2 (best 0.63) |
| 7TTC | Bamabcde bound to substrate espp | electron microscopy | P | — | — |
| 7YE4 | BAM-EspP complex structure with BamA-G431C and G781C/EspP-N1293C and A1043C mutations in nanodisc | electron microscopy | P | — | 6 (best 0.89) |
| 7YE6 | BAM-EspP complex structure with BamA-N427C/EspP-R1297C mutations in nanodisc | electron microscopy | P | — | 7 (best 0.77) |
| 8BNZ | BAM-EspP complex structure with BamA-G431C/EspP-N1293C mutations in nanodisc | electron microscopy | P | — | 6 (best 0.72) |
| 8BO2 | BAM-EspP complex structure with BamA-S425C/EspP-S1299C mutations in nanodisc | electron microscopy | P | — | — |
| 8Q0G | Release Complex: BAM bound EspP and Compact SurA | electron microscopy | P | — | 3 (best 0.82) |
| 8QP5 | Release Complex: BAM bound EspP (SurA released) | electron microscopy | P | — | 4 (best 0.79) |
| 8QPU | Release Complex: BAM bound EspP and Extended SurA | electron microscopy | P | — | 2 (best 0.82) |
| 8SPR | The cryo-EM structure of the EcBAM/EspP(beta1-12) complex | electron microscopy | F | — | 6 (best 0.80) |
| 8SQA | The cryo-EM structure of the EcBAM/EspP(beta8-12) complex | electron microscopy | F | — | 3 (best 0.74) |
| Q7BSW5 | AlphaFold monomer V2.0 prediction for serine protease espp (Q7BSW5) | predicted | A | — | — |
Experiment against prediction
- 3SLJ chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.08 Å
- 3SLJ chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.08 Å
- 3SLT chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.07 Å
- 3SLT chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.07 Å
- 3SLO chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.13 Å
- 3SLO chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.13 Å
- 3SZE chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.21 Å
- 3SZE chain A against the predicted model Q7BSW5: TM-score 0.98, RMSD 1.21 Å
- 8BO2 chain P against the predicted model Q7BSW5: TM-score 0.94, RMSD 1.81 Å
- 2QOM chain A against the predicted model Q7BSW5: TM-score 0.92, RMSD 1.57 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.