UniProt Q7BNC2
Beta-lactamase (Q7BNC2)
Beta-lactamase (UniProt Q7BNC2), EC 3.5.2.6: 11 experimental structures on GenesisL1, 8 ligands bound, 5 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- Q7BNC2
- Protein
- Beta-lactamase
- EC
- 3.5.2.6
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 8
- Pockets
- 5 · 1 record with a druggable one
Structures
11 records of Q7BNC2 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QNB | Crystal Structure of an Engineered OXA-10 Variant with Carbapenemase Activity, OXA-10loop24 | x-ray diffraction | A, B, C, D | — | — |
| 3QNB | Crystal structure of an engineered oxa-10 variant with carbapenemase activity, oxa-10LOOP24 | x-ray diffraction | A, B, C, D | — | — |
| 3QNC | Crystal Structure of a Rationally Designed OXA-10 Variant Showing Carbapenemase Activity… | x-ray diffraction | A, B | — | — |
| 3QNC | Crystal structure of a rationally designed oxa-10 variant showing carbapenemase activity… | x-ray diffraction | A, B | — | — |
| 6SKP | Oxa-10_IPM. structural insight to the enhanced carbapenem efficiency of oxa-655 compared to oxa-10. | x-ray diffraction | A, B | IM2, NA | — |
| 6SKR | Oxa-10_ETP. structural insight to the enhanced carbapenem efficiency of oxa-655 compared to oxa-10. | x-ray diffraction | A, B | MG | — |
| 6ZRG | Crystal structure of oxa-10LOOP48 in complex with hydrolyzed doripenem | x-ray diffraction | A, B | QP2, SO4, CL | — |
| 6ZRH | Crystal structure of oxa-10LOOP24 in complex with ertapenem | x-ray diffraction | A, B, C, D | 2RG | — |
| 6ZRI | Crystal structure of oxa-10LOOP24 in complex with meropenem | x-ray diffraction | A, B, C, D | — | — |
| 6ZW2 | Crystal structure of OXA-10loop48 in complex with hydrolyzed meropenem | x-ray diffraction | A, B | 8YL, SO4, CL | 5 (best 0.72) |
| 6ZW2 | Crystal structure of oxa-10LOOP48 in complex with hydrolyzed meropenem | x-ray diffraction | A, B | 8YL, SO4, CL | — |
Ligands
- CL · Chloride ion · in 3 records
- SO4 · Sulfate ion · in 3 records
- 8YL · (2S,3R)-2-[(2S,3R)-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3S,5S)-5-(dimethylcarbamoyl) pyrrolidin-3-yl]sulfan yl-3-methyl-2,3-dihydro-1H-pyrrole-5-carboxylic acid · in 2 records
- 2RG · (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl) carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid · in 1 record
- IM2 · (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carbox ylic acid · in 1 record
- MG · Magnesium ion · in 1 record
- NA · Sodium ion · in 1 record
- QP2 · (2~{S},3~{R})-4-[(3~{S},5~{S})-5-[[[azanyl-bis(oxidanyl)methyl]amino]methyl]pyrrolidin-3-yl]sulfanyl-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-3-methyl-2,3-dihydro-1~{H}-pyrrole-5-carboxylic acid · in 1 record
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.