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Ligand · 2RG

2RG · (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl) carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid

2RG, (2S,3R,4S)-4-({(3S,5S)-5-[(3-carboxyphenyl) carbamoyl]pyrrolidin-3-yl}sulfanyl)-2-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid (C22 H27 N3 O7 S, 477.5 g/mol), in the MolNFT structures on…

Component
2RG
Formula
C22 H27 N3 O7 S
Class
ligand
Structures
3
PDB entries
2

Binding sites

2RG in 3 structures; the first of them:

  • 6ZRH · Crystal structure of OXA-10loop24 in complex with ertapenem · 2RG A301 · binds ALA66, SER67, KCX70, MET99, TRP102, VAL114, SER115, VAL117 and 7 more
  • 6ZRJ · Crystal structure of class D Beta-lactamase OXA-48 in complex with ertapenem · 2RG A501 · binds ALA69, SER70, KCX73, ILE102, THR104, TRP105, TYR117, SER118 and 7 more
  • 6ZRH · Crystal structure of oxa-10LOOP24 in complex with ertapenem · 2RG A301 · binds ALA66, SER67, KCX70, TRP102, SER115, VAL117, LEU155, THR206 and 3 more

Residues it binds most

SER 14, LEU 14, THR 14, TRP 14, VAL 14, ARG 14, GLY 14, TYR 8, ALA 14, KCX 13 (residue and the binding sites it lines).

Found with

  • EDO · 1,2-ethanediol
  • CL · Chloride ion
  • PGE · Triethylene glycol

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