UniProt Q76LX8
A disintegrin and metalloproteinase with thrombospondin motifs 13 (Q76LX8)
A disintegrin and metalloproteinase with thrombospondin motifs 13 (UniProt Q76LX8), EC 3.4.24.87: 10 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 11 pockets. Binding sites, druggability and…
- UniProt
- Q76LX8
- Protein
- A disintegrin and metalloproteinase with thrombospondin motifs 13
- EC
- 3.4.24.87
- Experimental structures
- 10
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 11 · 1 record with a druggable one
Structures
11 records of Q76LX8 in the MolNFT archive: 10 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3GHM | Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-1) | x-ray diffraction | A | — | — |
| 3GHM | Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-1) | x-ray diffraction | A | — | — |
| 3GHN | Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-2) | x-ray diffraction | A | — | — |
| 3GHN | Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-2) | x-ray diffraction | A | — | — |
| 3VN4 | Crystal structure of the exosite-containing fragment of human ADAMTS13 (P475S mutant) | x-ray diffraction | A | — | — |
| 3VN4 | Crystal structure of the exosite-containing fragment of human ADAMTS13 (P475S mutant) | x-ray diffraction | A | — | — |
| 6QIG | Metalloproteinase | x-ray diffraction | A | NAG, FUC, ZN, CA, CL | 11 (best 0.71) |
| 6QIG | Metalloproteinase | x-ray diffraction | A | NAG, FUC, ZN, CA, CL | — |
| 7B01 | ADAMTS13-CUB12 | x-ray diffraction | A | NAG, GLC | — |
| 7B01 | ADAMTS13-CUB12 | x-ray diffraction | A | NAG, GLC | — |
| Q76LX8 | AlphaFold monomer V2.0 prediction for a disintegrin and metalloproteinase with thrombospondin… | predicted | A | — | — |
Ligands
Experiment against prediction
- 3GHM chain A against the predicted model Q76LX8: TM-score 0.96, RMSD 1.39 Å
- 3GHM chain A against the predicted model Q76LX8: TM-score 0.96, RMSD 1.39 Å
- 3VN4 chain A against the predicted model Q76LX8: TM-score 0.96, RMSD 1.44 Å
- 3VN4 chain A against the predicted model Q76LX8: TM-score 0.96, RMSD 1.44 Å
- 3GHN chain A against the predicted model Q76LX8: TM-score 0.91, RMSD 2.19 Å
- 3GHN chain A against the predicted model Q76LX8: TM-score 0.91, RMSD 2.19 Å
- 6QIG chain A against the predicted model Q76LX8: TM-score 0.89, RMSD 3.13 Å
- 6QIG chain A against the predicted model Q76LX8: TM-score 0.89, RMSD 3.13 Å
- 7B01 chain A against the predicted model Q76LX8: TM-score 0.37, RMSD 2.42 Å
- 7B01 chain A against the predicted model Q76LX8: TM-score 0.37, RMSD 2.42 Å
Elsewhere
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