UniProt Q72HR3
50S ribosomal protein L27 (Q72HR3)
50S ribosomal protein L27 (UniProt Q72HR3): 18 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q72HR3
- Protein
- 50S ribosomal protein L27
- Experimental structures
- 18
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 11 · 4 records with a druggable one
Structures
19 records of Q72HR3 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4V4I | Crystal Structure of a 70S Ribosome-tRNA Complex Reveals Functional Interactions and Rearrangements. | x-ray diffraction | U | — | — |
| 4V4J | Interactions and Dynamics of the Shine-Dalgarno Helix in the 70S Ribosome. | x-ray diffraction | U | — | — |
| 4V63 | Structural basis for translation termination on the 70S ribosome. | x-ray diffraction | B0, D0 | — | — |
| 4V67 | Crystal structure of a translation termination complex formed with release factor RF2. | x-ray diffraction | B0, D0 | — | — |
| 4V7P | Recognition of the amber stop codon by release factor RF1. | x-ray diffraction | BW, CW | — | — |
| 4V83 | Crystal structure of a complex containing domain 3 from the PSIV IGR IRES RNA bound to the 70S… | x-ray diffraction | BW, DW | — | — |
| 4V84 | Crystal structure of a complex containing domain 3 of CrPV IGR IRES RNA bound to the 70S ribosome. | x-ray diffraction | BW, DW | — | — |
| 4V9J | 70S ribosome translocation intermediate GDPNP-II containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | B0, D0 | — | — |
| 4V9K | 70S ribosome translocation intermediate GDPNP-I containing elongation factor EFG/GDPNP, mRNA, and… | x-ray diffraction | B0, D0 | — | — |
| 4V9L | 70S Ribosome translocation intermediate FA-3.6A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | B0, D0 | — | — |
| 4V9M | 70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP… | x-ray diffraction | B0, D0 | — | — |
| 4V9N | Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2. | x-ray diffraction | B0, D0 | — | — |
| 4V9Q | Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. | x-ray diffraction | AW, CW | — | — |
| 4XEJ | IRES bound to bacterial Ribosome | x-ray diffraction | AL27, BL27 | — | 2 (best 0.87) |
| 5V8I | Thermus thermophilus 70S ribosome lacking ribosomal protein uS17 | x-ray diffraction | 10, 20 | MG | 4 (best 0.89) |
| 6B4V | Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome | x-ray diffraction | X, BC | BLS, MG | 2 (best 0.86) |
| 6BOH | Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound to the… | x-ray diffraction | X, CC | MG | 3 (best 0.88) |
| 6BOK | E. coli release factor 1 (containing deletion 302-304) bound to the 70S ribosome | x-ray diffraction | X, AC | MG | — |
| Q72HR3 | AlphaFold monomer V2.0 prediction for 50S ribosomal protein L27 (Q72HR3) | predicted | A | — | — |
Ligands
Experiment against prediction
- 5V8I chain 20 against the predicted model Q72HR3: TM-score 0.98, RMSD 0.52 Å
- 5V8I chain 10 against the predicted model Q72HR3: TM-score 0.97, RMSD 0.57 Å
- 4V9N chain B0 against the predicted model Q72HR3: TM-score 0.96, RMSD 0.70 Å
- 4V84 chain BW against the predicted model Q72HR3: TM-score 0.96, RMSD 0.67 Å
- 4V9Q chain AW against the predicted model Q72HR3: TM-score 0.96, RMSD 0.74 Å
- 4V83 chain BW against the predicted model Q72HR3: TM-score 0.96, RMSD 0.73 Å
- 4V67 chain B0 against the predicted model Q72HR3: TM-score 0.95, RMSD 0.76 Å
- 4V7P chain BW against the predicted model Q72HR3: TM-score 0.95, RMSD 0.76 Å
- 4V63 chain B0 against the predicted model Q72HR3: TM-score 0.95, RMSD 0.77 Å
- 4XEJ chain AL27 against the predicted model Q72HR3: TM-score 0.95, RMSD 0.80 Å
Elsewhere
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