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Ligand · BLS

BLS · Blasticidin S

BLS, Blasticidin S (C17 H26 N8 O5, 422.4 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
BLS
Formula
C17 H26 N8 O5
Class
ligand
Structures
6
PDB entries
6

Binding sites

BLS in 6 structures; the first of them:

  • 6B4V · Antibiotic blasticidin S and E. coli release factor 1 bound to the 70S ribosome · BLS B9001 · binds C2063, C2064, C2065, OMG2251, G2252, U2438, A2439, A2600 and 6 more
  • 6BOH · Antibiotic blasticidin S and E. coli release factor 1 (containing deletion 302-304) bound… · BLS B9001 · binds C2063, C2064, C2065, OMG2251, G2252, U2438, A2439, A2600 and 5 more
  • 7NWG · Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by… · BLS 515294 · binds C3909, C3910, G4196, G4197, U4384, A4385, A4546, C4547 and 3 more
  • 7NWH · Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. · BLS 55122 · binds C3909, G4196, G4197, A4385, A4546, C4547, A4548
  • 7NWI · Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S · BLS 55241 · binds VAL68, A76, C3909, C3910, G4196, G4197, U4384, A4385 and 2 more
  • 7Q0R · Structure of the Candida albicans 80S ribosome in complex with blasticidin s · BLS 13403 · binds C2383, C2384, G2591, G2592, U2779, A2780, A2941, C2942

Residues it binds most

C 8, A 8, G 8, U 7, OMG 4, ALA 2, VAL 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • MG · Magnesium ion
  • GCP · Phosphomethylphosphonic acid guanylate ester
  • SPD · Spermidine

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