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UniProt Q6ZXT3

Aquaglyceroporin 2 (Q6ZXT3)

Aquaglyceroporin 2 (UniProt Q6ZXT3): 6 experimental structures on GenesisL1, 3 ligands bound, 33 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
Q6ZXT3
Protein
Aquaglyceroporin 2
Experimental structures
6
Predicted models
0
Ligands
3
Pockets
33 · 6 records with a druggable one

Structures

6 records of Q6ZXT3 in the MolNFT archive: 6 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8JY6Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprolelectron microscopyA, B, C, DL1U10 (best 0.86)
8JY7Structure of the TbAQP2 in the apo conformationelectron microscopyA, B, C, D—10 (best 0.86)
8JY8Structure of TbAQP2 in complex with anti-trypanosomatid drug pentamidineelectron microscopyA, B, C, DPNT10 (best 0.86)
8OFXMolecular Mechanism of trypanosomal AQP2electron microscopyAVO61 (best 0.73)
8OFYMolecular Mechanism of trypanosomal AQP2electron microscopyAPNT1 (best 0.75)
8OFZMolecular Mechanism of trypanosomal AQP2electron microscopyA—1 (best 0.71)

Ligands

  • PNT · 1,5-bis(4-amidinophenoxy)pentane · in 2 records
  • L1U · [(4~{R})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol · in 1 record
  • VO6 · [(2~{R},4~{S})-2-[4-[[4,6-bis(azanyl)-1,3,5-triazin-2-yl]amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol · in 1 record

Elsewhere

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