UniProt Q6ZNE5
Beclin 1-associated autophagy-related key regulator (Q6ZNE5)
Beclin 1-associated autophagy-related key regulator (UniProt Q6ZNE5): 4 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- Q6ZNE5
- Protein
- Beclin 1-associated autophagy-related key regulator
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 9 · 2 records with a druggable one
Structures
5 records of Q6ZNE5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6HOL | Structure of ATG14 LIR motif bound to GABARAPL1 | x-ray diffraction | C, D | — | — |
| 6HOL | Structure of ATG14 lir motif bound to GABARAPL1 | x-ray diffraction | C, D | — | — |
| 8SOR | Structure of human PI3KC3-C1 complex | electron microscopy | C | — | 5 (best 0.74) |
| 9C82 | Structure of human ULK1C:PI3KC3-C1 supercomplex | electron microscopy | C | — | 4 (best 0.83) |
| Q6ZNE5 | AlphaFold monomer V2.0 prediction for beclin 1-associated autophagy- related key regulator (Q6ZNE5) | predicted | A | — | — |
Experiment against prediction
- 8SOR chain C against the predicted model Q6ZNE5: TM-score 0.83, RMSD 2.25 Å
- 9C82 chain C against the predicted model Q6ZNE5: TM-score 0.75, RMSD 3.56 Å
- 6HOL chain C against the predicted model Q6ZNE5: TM-score 0.48, RMSD 0.85 Å
- 6HOL chain C against the predicted model Q6ZNE5: TM-score 0.48, RMSD 0.85 Å
- 6HOL chain D against the predicted model Q6ZNE5: TM-score 0.46, RMSD 0.99 Å
- 6HOL chain D against the predicted model Q6ZNE5: TM-score 0.46, RMSD 0.99 Å
Elsewhere
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