UniProt Q6UX46

ALK and LTK ligand 2 (Q6UX46)

ALK and LTK ligand 2 (UniProt Q6UX46): 5 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt: Q6UX46
Protein: ALK and LTK ligand 2
Experimental structures: 5
Predicted models: 1
Ligands: 1

Structures

6 records of Q6UX46 in the MolNFT archive: 5 experimental, 1 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
7LS0	Structure of the human ALK grd bound to aug	x-ray diffraction	A, B, C, D	NAG	—
7MZX	AUGalpha - FAM150B - ALKL2 77-152	solution nmr	A	—	—
7MZX	Augalpha - FAM150B - ALKL2 77-152	solution nmr	A	—	—
7N00	Anaplastic lymphoma kinase (ALK) extracellular fragment of ligand binding region 648-1025 in…	electron microscopy	B, D	—	—
7NWZ	ALK:ALKAL2 complex	x-ray diffraction	D, C	—	—
Q6UX46	AlphaFold monomer V2.0 prediction for ALK and ltk ligand 2 (Q6UX46)	predicted	A	—	—

Ligands

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 1 record

Experiment against prediction

7NWZ chain C against the predicted model Q6UX46: TM-score 0.93, RMSD 0.78 Å
7NWZ chain D against the predicted model Q6UX46: TM-score 0.93, RMSD 0.77 Å
7N00 chain B against the predicted model Q6UX46: TM-score 0.91, RMSD 0.84 Å
7LS0 chain D against the predicted model Q9UM73: TM-score 0.91, RMSD 2.61 Å
7N00 chain D against the predicted model Q6UX46: TM-score 0.90, RMSD 0.88 Å
7LS0 chain C against the predicted model Q9UM73: TM-score 0.90, RMSD 2.69 Å
7LS0 chain B against the predicted model Q9UM73: TM-score 0.90, RMSD 2.91 Å
7LS0 chain A against the predicted model Q9UM73: TM-score 0.89, RMSD 2.90 Å
7MZX chain A against the predicted model Q6UX46: TM-score 0.74, RMSD 1.98 Å
7MZX chain A against the predicted model Q6UX46: TM-score 0.74, RMSD 1.98 Å

Elsewhere

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